Knee Tendinopathy | Tendinosis | Tendonitis
Research continues to support the use of Platelet Rich Plasma Therapy in the treatment of knee tendinopathies. Recent research has found:
- Platelet Rich Plasma Therapy is effective for knee tendinopathy.1
- Platelet Rich Plasma Therapy is effective not only for knee tendinopathy but also elbow, shoulder, and Achilles tendon problems,2 and other tendon problems.3
- New research shows that a single local injection of PRP coupled with a program of eccentric rehabilitation for treating a chronic jumper’s knee, improves pain symptoms and the functionalities of the subjects’ knee up to 1 year after injection.4
Tendonitis is the most common injury to the knee, although not the most well-known one. In general, it refers to an inflammation, irritation or tear of a tendon, the thick fibrous cords that attach muscles to bone. One of the most frequent types of tendonitis of the knee is pes anserinus tendonitis, which involves the pes anserinus tendons that lie on the inside and just below the knee joint and prevents the lower leg from twisting outward while running.
Middle-aged adult runners are most susceptible to the development of pes anserinus tendonitis, the most common form. Two other types of knee tendonitis are popliteus tendonitis and semimembranous tendonitis.
Patellar tendonitis is inflammation of the patellar tendon, which attaches the kneecap to the tibia or shinbone.The patellar tendon helps your muscles extend your knee.
Popliteus tendonitis is caused by excessive inward rolling of the feet, called pronation, as well as running downhill, which tends to put excessive stress on this tendon and can cause it to tear or become inflamed. Pes anserine tendonitis, on the other hand, is characterized by inflammation of the medial knee, and often coexists with other knee disorders. Semimembranous tendonitis is characterized by swelling over the posteromedial aspect of the knee and tenderness with resisted flexion or outward-turned strain.
Patellar tendonitis is an acute condition, such as knee pain following a run. If the tendon is stressed repeatedly, tiny tears can occur in the tendon. If this process persists, the tendon degenerates causing tendinosis.
Knee tendonitis in general produces pain, tenderness and stiffness near a joint and is aggravated by movement. The inflamed tendons in the knee are usually painful when moved or touched, and the tendon sheaths may be visibly swollen from the accumulation of fluid and inflammation. Moving the joints near the tendon even slightly may also cause severe pain. The pain may be worse when ascending or descending stairs, when getting up from a seated position, and at night.
For the most part, medical intervention, is not needed as the tendon will usually heal itself. HOWEVER, some times the tendon inflammation does not abade and chronic pain develops, This is refered to as chronic tendonitis where inflammation is constantly present or tendonosis where inflammation has given up trying to mend the tendon and joint weakness, mobility issues, and pain persists on a permananet basis.
Most recently, the medical literature began describing problems of the tendons as simply “tendinopathy” or “tendinopathies,” disease of the tendon(s).
Treatments for knee tendinopathies
The typical treatment regime for tendonitis, such as knee tendonitis, rotator cuff tendonitis or patellar tendonitis, includes RICE therapy, ice, non-steroidal anti-inflammatory drugs (NSAIDs), physical therapy and cortisone injections. The problem with this approach is that they do not regenerate or rebuild the weakened tendon and, thus, does not alleviate the chronic pain that people with this condition experience. While ice, anti-inflammatory drugs and cortisone shots have been shown to produce short-term pain benefit, they result in long-term loss of function and even more chronic pain by actually inhibiting the healing process of soft tissues and accelerating cartilage degeneration. If the individual with tendonitis receives cortisone injections into the tendon, or if they take anti-inflammatories for a very long time, the tendonitis will become tendinosis. This means the tendon becomes degenerated.
Other treatment options include cryotherapy and massage. But again, although they may provide pain relief, they do not address the root of the problem – weakened and/or injured tendons and ligaments. When the patient tries these treatment modalities and the pain persists, patients who experience tendonitis may be referred to a surgeon. Unfortunately, surgery has consequences and side effects and may make the problem worse.
Tendonitis is a confusing diagnosis
New research says imaging studies confuse the diagnosis.
Damage of the tendon (Tendinopathy) is frequently diagnosed and managed with the clinical use of ultrasound and magnetic resonance imaging. However, similar to other musculoskeletal conditions (osteoarthritis and intervertebral disc degeneration) there is no direct link between what the MRI says and clinical symptoms, with findings on imaging potentially creating a confusing clinical picture.5
Using Prolotherapy as a regenerative treatment for tendonitis
In treating tendonitis, which is occasionally misdiagnosed as bursitis, we recommend stimulating tendon repair and strengthening any weakened or lax ligaments with MEAT treatment, which consists of movement, exercise, analgesics and treatment, as well as herbal supplements. This approach will encourage the damaged tissues to heal as quickly as possible.
Prolotherapy and Platelet Rich Plasma Therapy
Comprehensive Prolotherapy to the knee involves multiple injections of a dextrose-based solution directed at the affected tendons, ligaments and other affected structures of the knee. This causes a mild and localized inflammatory response which triggers the immune system to initiate repair of the injured tendons and ligaments. Blood supply dramatically increases at the injured area. The body is alerted that healing needs to take place and reparative cells are sent to the treated area of the knee that needs healing. The body also lays down new collagen at the treated areas, thereby strengthening the weakened structures. Once the tendons and ligaments are strengthened, the joint stabilizes and the tendonitis or tendinosis condition resolves.
Platelet Rich Plasma Therapy is the use of a patient’s blood platelets and healing factors to stimulate repair of a tendon it is considered when tendon damage is more severe.
As mentioned tendonitis usually does not require Prolotherapy, while tendinosis, the degeneration of the tendon, benefits tremendously from Prolotherapy. However, with tendonitis, if the tendon does not continue to improve every week or if a tendonitis injury requires extra-quick healing, such as is the case with many athletes, Prolotherapy can be performed. When the tendon cannot heal on its own, an underlying ligament problem and joint instability may be occurring, allowing for too much movement of the knee joint. This movement irritates the tendon because the tendon is unable to contract against a stable knee. Prolotherapy strengthens the weakened tendons and ligaments.
1. Lubowitz JH. Editorial commentary: biologic enhancement of muscle and tendon healing. Arthroscopy. 2015 May;31(5):1016. doi: 10.1016/j.arthro.2015.02.037.
2. Nourissat G, Ornetti P, Berenbaum F, Sellam J, Richette P, Chevalier X. Does platelet-rich plasma deserve a role in the treatment of tendinopathy? pii: S1297-319X(15)00048-2. doi: 10.1016/j.jbspin.2015.02.004. [Epub ahead of print] Joint Bone Spine. 2015 Apr 13.
3. Sanli I, Morgan B, van Tilborg F, Funk L, Gosens T. Single injection of platelet-rich plasma (PRP) for the treatment of refractory distal biceps tendonitis: long-term results of a prospective multicenter cohort study. Knee Surg Sports Traumatol Arthrosc. 2014 Dec 11. [Epub ahead of print]
4. Kaux JF, Bruyere O, Croisier JL, Forthomme B, Le Goff C, Crielaard JM. One-year follow-up of platelet-rich plasma infiltration to treat chronic proximal patellar tendinopathies. Acta Orthop Belg. 2015 Jun;81(2):251-6.
5.Docking SI, Ooi CC, Connell D. Tendinopathy: Is Imaging Telling Us the Entire Story?
J Orthop Sports Phys Ther. 2015 Sep 21:1-27