Caring Medical - Where the world comes for ProlotherapyPost-concussion syndrome


In this article, Ross Hauser, MD., discusses Prolotherapy injection treatments to the neck to help patients suffering from post concussion syndrome.

There is research that can be somewhat alarming to patients and their families where post-concussion syndrome is present. Published in the medical journal Brain Injury – doctors of  the American College of Sports Medicine (ACSM) say a standard definition of Post-concussion Syndrome (PCS) does not exist.

When the doctors in the study asked what would be the minimum number of symptoms required to diagnose PCS, responses varied:

So presenting to one doctor one symptom would get a diagnosis of post-concussion syndrome, while going to a second doctor for a second opinion who believes that there are three symptoms needed will not.

Should a patient suffering from an apparent post-concussion syndrome ask the doctors first, how many symptoms do I need to be diagnosed, in your opinion?

However, this next piece of research can make for a fascinating revelation and a great understanding of how to treat the post-concussion syndrome patient. Notice that in this study, the obvious treatment recommendation, in my opinion, is not mentioned but certainly alluded to.

In new research, doctors questioned the traditional diagnostic tools of determining post-concussion syndrome. The doctors noted that approximately 90% of concussions are transient, with symptoms resolving within 10-14 days. However, a minority of patients remain symptomatic several months post-injury and that the treatment of these patients can be challenging.2,3

The goal of this study was to assess the usefulness and cost-effectiveness of neurologic imaging two or more weeks post-injury in youth athletes with post-concussion syndrome (PCS).

Here are the numbers:

Of 52 patients with PCS, 23 of 52 (44 %) had neuroimaging at least 2 weeks after the initial injury, for a total of 32 diagnostic studies.

Read the conclusion
“brain imaging in the chronic phase (defined as more than 2 weeks after concussion) was pursued in almost half the study sample, had low diagnostic yield, and had poor cost-effectiveness. Based on these results, outpatient management of pediatric patients with long-term post-concussive symptoms should rarely include repeat neuroimaging beyond the acute phase.4

So what should be said here? The problems of long-term PCS should not be confined or even be supported by  brain imaging because images will not help and may hinder treatment of PCS symptoms.

In other words – you need to look somewhere else to help these people. That place is the cervical neck ligaments.

Cluster Post-concussion syndrome symptoms

When the brain is subjected to a violent force, it can bleed, swell and, occasionally, shut down. In addition, PCS can manifest itself as chronic pain in the form of headaches and neck pain, following a concussion or MTBI Mild Traumatic Brain Injury.

Symptoms vary from patient to patient but can include

These symptoms can range in severity from being slightly annoying to becoming an overwhelming disability.

Post-Concussion Syndrome Treatments

After an MRI to rule out the existence of a hematoma, doctors usually try a number of different approaches to deal with the headache and pain. “The primary forms of PCS treatment have traditionally included rest, education, neurocognitive rehabilitation, and antidepressants, with little evidence of success.”5,6

Pain control may also be approached using nerve blocks or transcutaneous electrical nerve stimulation (TENS), which involves the electrical stimulation of muscle groups. These modalities might provide temporary relief, but they only modify symptoms and usually do not address the root cause of chronic pain and symptoms associated with post-concussion syndrome.

Treatment to the Neck

Treatment approaches depend on the clinician’s ability to differentiate among the various conditions associated with PCS. As with any approach to a chronically painful condition, the first step in treating post-concussion syndrome is to identify the cause, taking into account the structures that may have been injured as a result of the jarring motion of the head.

It’s quite possible that the cause of post concussion syndrome may be due to injured neck ligaments. “After the neurologic examination, the cervical spine should be carefully assessed for tenderness, spasm, and range of motion. Precipitation of headaches, dizziness, or vertigo should direct therapy to address a cervical injury.”6

If cervical injury is diagnosed, treatment would involve correcting the alignment of the vertebrae in the neck posteriorly, so they no longer pinch the sympathetic nerves. This can be accomplished with Prolotherapy treatments. In our own research from Caring Medical lead by Danielle Steilen, cites that treating the capsular ligaments of the neck which are the main stabilizing structures of the facet joints in the cervical spine and have been implicated as a major source of chronic neck pain – we can stabilize the neck and symptoms not only of neck pain, but of post concussion syndrome as well.

When the capsular ligaments are injured, they become elongated and exhibit laxity (weakness), which causes excessive movement of the cervical vertebrae. In the upper cervical spine (C0-C2), this can cause a number of other symptoms including, but not limited to, nerve irritation and vertebrobasilar insufficiency with associated vertigo, tinnitus, dizziness, facial pain, arm pain, and migraine headaches.

In the lower cervical spine (C3-C7), this can cause muscle spasms, crepitation, and/or paresthesia in addition to chronic pain.

In either case, the presence of excessive motion between two adjacent cervical vertebrae and these associated symptoms is described as cervical instability.  We contend that prolotherapy offers a potentially curative treatment option for chronic pain related to capsular ligament laxity and underlying cervical instability.

The areas to be treated with Prolotherapy are determined by palpatory examination. Using this method we find that the accuracy in diagnosing the actual pain-producing area is excellent. Once identified these tender areas are treated with Prolotherapy injections.

1. Rose SC, Fischer AN, Heyer GL. How long is too long? The lack of consensus regarding the post-concussion syndrome diagnosis. Brain Inj. 2015 Apr 14:1-6. [Epub ahead of print]
2. King NS. Post-concussion syndrome: clarity amid the controversy?The British Journal of Psychiatry. 2003; 183: 276-278. doi: 10.1192/02-471
3. Sterr A, Herron KA, Hayward C, Montaldi D. Are mild head injuries as mild as we think? Neurobehavioral concomitants of chronic post-concussion syndrome. BMC Neurology. 2006; 6:7.  doi:10.1186/1471-2377-6-7
4. Morgan CD, Zuckerman SL, King LE, Beaird SE, Sills AK, Solomon GS. Post-concussion syndrome (PCS) in a youth population: defining the diagnostic value and cost-utility of brain imaging. Childs Nerv Syst. 2015 Dec;31(12):2305-9. doi: 10.1007/s00381-015-2916-y. Epub 2015 Sep 29.
5. Leddy JJ, Sandhu H, Sodhi V, Baker JG, Willer B. Rehabilitation of Concussion and Post-concussion Syndrome. Sports Health. 2012; 4(2): 147–154. doi:  10.1177/1941738111433673
6. Leddy JJ, Kozlowski K, Donnelly JP, Pendergast DR, Epstein LH, Willer B. A Preliminary Study of Subsymptom Threshold Exercise Training for Refractory Post-Concussion Syndrome. Clin J Sport Med.  2010; 20: 21–27.
9. Steilen D, Hauser R, Woldin B, Sawyer S. Chronic neck pain: making the connection between capsular ligament laxity and cervical instability. Open Orthop J. 2014 Oct 1;8:326-45. doi: 10.2174/1874325001408010326. eCollection 2014.

How Can We Help You?
Contact Information:
First Name*:
Last Name*:
How did you hear about us?
Are you looking for more information on our specialties?
I am interested in ProlotherapyI am interested in Stem Cell TherapyI am interested in Platelet Rich PlasmaI am looking for a potential alternative to surgeryI am interested in Digital Motion X-ray in Florida
Tell us more about your case:
Current diagnoses by another healthcare provider:
My primary medical concern I would like to inquire about*:
My current level of athletics and/or daily activities
(ie: marathon training, manual labor, etc..):
I am interested in an appointment at this location:
Oak Park, IllinoisFort Myers, Florida
as soon as possiblewithin a couple weekswithin 1-2 monthsnot sure
Please leave this field empty.

for your symptoms

Prolotherapy, an alternative to surgery

Were you recommended SURGERY?
Get a 2nd opinion now!

★ ★ ★ ★ ★We pride ourselves on 5-Star Patient Service!Come see why patients travel from all
over the world to visit our clinics.
Current Patients
Become a New Patient

Chicagoland Office
715 Lake St., Suite 600
Oak Park, IL 60301
(708) 393-8266 Phone
(855) 779-1950 Fax
Southwest Florida Office
9738 Commerce Center Ct.
Fort Myers, FL 33908
(239) 303-4069 Phone
(855) 779-1950 Fax Fort Myers, FL Office
© 2017 | All Rights Reserved | Disclaimer
National Prolotherapy Centers specializing in Comprehensive Prolotherapy,
Stem Cell Therapy, and Platelet Rich Plasma.

Meet our Prolotherapy Doctors and check out our Prolotherapy research.