What is Platelet Rich Plasma
Platelet Rich Plasma – Prolotherapy using your own growth factors
At Caring Medical, we specialize in proliferative injection therapies, known as Prolotherapy. While these regenerative medicine treatments have been around for many decades, one of the exciting additions, in recent years, is Platelet Rich Plasma (PRP). PRP works great for a number of conditions, particularly labral tears of the hip and shoulder, as well as degenerated meniscus and meniscus tears. If you have a nagging injury, or are looking for an alternative to labral surgery or other surgical procedure, this section will teach more about PRP and how we may help your injury heal faster using comprehensive Prolotherapy with PRP (PRPP).
What are platelets in our blood used for?
Platelets play a central role in blood clotting and wound healing. Tissue repair begins with clot formation and platelet degranulation, which release the growth factors necessary for wound repair. Platelet-derived growth factors are biologically active substances that enhance tissue repair mechanisms. After platelets are activated at a wound site, proteins are released that directly and indirectly influence virtually all aspects of the wound healing cascade. Studies have shown a direct correlation between the platelet concentration and the level of secretory proteins, as well as the amount of proliferation involved in the wound healing.
How does Platelet Rich Plasma work?
In basic terms, PRP involves the application of concentrated platelets, which release a supra-maximal quantity of growth factors which stimulate recovery in non-healing injuries. PRP causes a mass influx of growth factors, such as platelet-derived growth factor, transforming growth factor and others, which exert their effects of fibroblasts causing proliferation and thereby accelerating the regeneration of injured tissues. Specifically, PRP enhances the fibroblastic events involved in tissue healing including chemotaxis, proliferation of cells, proteosynthesis, reparation, extracellular matrix deposition, and the remodeling of tissues. Bottom line here is that tissues can heal faster with Platelet Rich Plasma treatment.
How are PRP injections performed?
PRP Prolotherapy is performed at Caring Medical by our Prolotherapy injection specialists, Ross Hauser, MD and Danielle Steilen, MMS, PA-C. The preparation of therapeutic doses of growth factors consists of an autologous blood collection (blood from the patient), plasma separation (blood is centrifuged), and application of the plasma rich in growth factors (injecting the plasma into the area.) In other words, a PRP treatment is done just like any other Prolotherapy treatment, except the solution used for injection is plasma enriched with growth factors from your own blood. In our office, patients are generally seen every 4-6 weeks. Typically three to six visits are necessary per area.
What conditions are treated with Platelet Rich Plasma?
In the scientific literature are reports of soft tissue injuries treated with PRP including tendinopathy, tendinosis, acute and chronic muscle strain, muscle fibrosis, ligamentous sprains and joint capsular laxity. Platelet Rich Plasma – PRP has also been utilized to treat intra-articular injuries. Examples include arthritis, arthrofibrosis, articular cartilage defects, meniscal injury, and chronic synovitis or joint inflammation.
PRP has been used successfully to enhance surgical outcomes in maxillofacial, cosmetic, spine, orthopedic, and podiatric surgery. In regard to its use today, you will see that the majority of doctors using it apply it onto their current knowledge base of Prolotherapy. In other words, the doctors doing PRP are using it as a proliferant, much like they use other solutions in Prolotherapy. In simple terms, PRP is a type of Prolotherapy!