Bone Marrow Aspirate Prolotherapy for knee pain

Katherine L. Worsnick, MPAS, PA-C  and Ross Hauser MD

In this article we will present clinical research and case studies to support the use of Bone Marrow Aspirate for Knee Pain.

Bone Marrow Aspirate or Bone Marrow Prolotherapy refers to the use of bone marrow concentrate injections into areas of degenerative joint disease to stop and repair degenerative changes.

Bone Marrow Aspirate therapy is often called bone marrow stem cell therapy or simply stem cell therapy. The technique as utilized here at Caring Medical for our patients is described in the video below.

Understanding the technique of Bone Marrow Aspirate therapy is to understand that there are many variations of this therapy. Not all doctors utilize bone marrow stem cells in the same way. There is even variations in the way the effectiveness of Bone Marrow Aspirate therapy is reported in the medical literature.

Here is what researchers wrote in the Orthopaedic journal of sports medicine:

“Although a growing interest for biological alternatives of treating knee pathology has been observed in the past few years, there still remains a paucity of high-quality studies. The studies included in this systematic review reported varying degrees of beneficial results with the use of Bone Marrow Aspirate with and without an additional procedure for the treatment of chondral defects and early stages of osteoarthritis. Most articles present the use of Bone Marrow Aspirate  as a safe procedure and report good results.”(1)

Caring Medical Research and case histories:

In the medical journal Clinical medicine insights. Arthritis and musculoskeletal disorders our team presented the following case histories:

Case history 1

Case history 2

Case history 3

Would you like to ask a question about Bone marrow stem cell therapy for knee pain? Ask our Caring Medical staff

1 Chahla J, Dean CS, Moatshe G, Pascual-Garrido C, Serra Cruz R, LaPrade RF. Concentrated bone marrow aspirate for the treatment of chondral injuries and osteoarthritis of the knee: a systematic review of outcomes. Orthopaedic journal of sports medicine. 2016 Jan 13;4(1):2325967115625481. [Google Scholar]

2. Hauser RA, Orlofsky A. Regenerative injection therapy with whole bone marrow aspirate for degenerative joint disease: a case series. Clin Med Insights Arthritis Musculoskelet Disord. 2013 Sep 4;6:65-72. Google Scholar


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