Caring Medical - Where the world comes for ProlotherapyIschial tuberosity pain and ischiofemoral impingement

Ross Hauser, MD

In this article we will describe Ischial tuberosity pain and ischiofemoral impingement. Focus will be on two types of problems. Impingement caused by instability and non or malunion of the fragment of the Ischial tuberosity caused by apophyseal (growth plate) avulsion fractures in young athletes.

When a person has severe buttock pain along with tenderness on the ischial tuberosity, often the diagnosis of ischial tuberosity pain syndrome or ischial bursitis is made. Bursitis can be ruled out when the area is not significantly red and swollen.

When MRIs are performed of this area, occasionally they show tendinosis or degenerated tendon (it is actually the hamstring muscle origin) but more often than not, the MRI is negative. Why is this? MRIs can never show weakness in a tissue. When you can stand and your butt no longer hurts, but then it significantly irritates you the more you sit, then clearly the structures you are sitting on do not have the strength to withstand the pressure of sitting.

What are the structures?

The ischial tuberosity is a strong, widening of the bone on either side of the frontal portion of the ischium, the lowest of the three major bones that make up each half of the pelvis.

As the point of fusion of the ischium and the pubis, it is attached to various muscles and supports the weight of the body when one is sitting. The Ischial tuberosity is commonly referred to as the “sit bones.”

The ischial tuberosity is where the adductor and hamstring muscles of the thigh, as well as the sacrotuberus ligaments attach. The forceful pull of these muscles, may result in avulsion fracture, where a piece of the bone is pulled off during a trauma/impact injury (see below for our discussion on avulsion fractures).

Ischiofemoral impingement

Pelvic Instability

Doctors in Spain published their findings on Ischiofemoral impingement syndrome. They describe it as:

  • An under-recognized hip impingement problem defined by hip pain related to narrowing of the space between the ischial tuberosity and the femur which causes a pinching of the soft tissue between the bones.
  • The causes of ischiofemoral impingement is multifactorial (note in the original research how many times the word instability is used – clearly the problem is joint instability). Here is their list:

Various impingement syndromes are discussed by Ross Hauser, MD

Prolotherapy and Conservative Treatments for Impingement

The traditional conservative treatment route prescribes the RICE protocol, which consists of rest, ice, compression and elevation. The problem with this approach is that it does not repair the injured tissue of the hamstring tendons, the tendon attachments and support ligaments.

  • Rest and ice are particularly serious culprits when it comes to soft tissue damage because they decrease circulation to the area, which hinders rather than helps the healing process.
  • Physical therapy is commonly ordered and has its place for the treatment of ischial tuberosity pain, but once again, does not address the issue of weak or injured ligaments or tendon attachments.
  • Steroid injections and anti-inflammatory medications are another standard recommendation. These treatments may provide short term relief, however, in the long run do more damage than good.

Prolotherapy is a regenerative treatment that successfully treats ischial tuberosity pain. Prolotherapy injections to the sacrotuberous ligaments and the hamstring tendon attachment will stimulate repair of these damaged areas. A comprehensive exam by the experienced Prolotherapist is vital for a thorough treatment. Sometimes pain in other areas is also involved. For instance, pain in the ischial tuberosities may be coupled with pain in the pubic symphysis. There may also be pain in the sacroiliac joints. A comprehensive Prolotherapy treatment will include all of the weakened or injured areas.

Prolotherapy for ischial tuberosity pain involves injections of a dextrose solution which causes a mild inflammatory reaction at the weakened areas. This initiates a wound cascade that includes an increase of blood flow and immune cells to the treated area. There will be an influx of reparative cells and a deposition of collagen to repair the injured ligaments and attachments. Once this soft tissue is strengthened, the sacrotuberous ligaments and the hamstring tendon attachment and other involved soft tissue will now be strong and stable, and the ischial tuberosity pain will resolve.

In a case study presented by doctors at the Chung-Ang University College of Medicine in South Korea and published in the medical journal Pain Practice, the doctors of the study showed that they effectively treated two male patients using ultrasound-guided prolotherapy.

  • A 24-year-old male patient with no history of trauma or surgery complained of bilateral hip and groin pain; magnetic resonance imaging demonstrated slight narrowing of the bilateral ischiofemoral spaces with mild enhancement of the left quadratus femoris muscle.
  • A 23-year-old male patient with a history of iliotibial band release and iliopsoas tendon release complained of left hip and groin pain; magnetic resonance imaging revealed swelling of the left quadratus femoris muscle.

After the fifth treatment session of prolotherapy, the pain severity score using the visual analog scale was found to be minimal (0-1/10), and follow-up magnetic resonance imaging revealed a slightly decreased enhancement of the quadratus femoris muscle compared with that on previous images.

The researchers concluded: “Prolotherapy was an efficacious treatment for two patients with ischiofemoral impingement syndrome who were not candidates for surgery.”2

Special note on Dysfunction after malunion or non-union of ischial tuberosity apophyseal avulsion fractures

  • Doctors at the Mayo Clinic examined ten patients (age 14 to 28) who underwent surgery for recurring hip and buttock pain following a prior ischial tuberosity avulsion fracture.
  • The malunion or non-union following ischial tuberosity apophyseal (growth plate) fracture can lead to ischiofemoral impingement and hamstring dysfunction. The pain and dysfunction is often chronic, and can be debilitating. In select cases, a reliable surgical technique is presented to improve hamstring function and correct ischiofemoral impingement in this setting with good-to-excellent outcomes in the majority of cases at short-term follow-up.
  • Five patients (50 %) rated their hip as normal, and five patients (50 %) rated their hip as near normal a little more than two years after surgery.2

In this situation, where weakness exists after surgery, a Prolotherapy consultation may assist the young athlete or patient following surgery strengthen the tendon and ligament attachments that may cause instability.

If you have questions about Ischial tuberosity pain and ischiofemoral impingement, get help and information from Caring Medical

1 Hernando MF, Cerezal L, Pérez-Carro L, Canga A, González RP. Evaluation and management of ischiofemoral impingement: a pathophysiologic, radiologic, and therapeutic approach to a complex diagnosis. Skeletal Radiol. 2016 Jun;45(6):771-87. doi: 10.1007/s00256-016-2354-2. Epub 2016 Mar 3. [Pubmed] [Google Scholar]

2 Kim WJ, Shin HY, Koo GH, Park HG, Ha YC, Park YH. Ultrasound‐guided Prolotherapy with Polydeoxyribonucleotide Sodium in Ischiofemoral Impingement Syndrome. Pain Practice. 2014 Sep 1;14(7):649-55. [Pubmed] [Google Scholar]

3 Spencer-Gardner L, Bedi A, Stuart MJ, Larson CM, Kelly BT, Krych AJ. Ischiofemoral impingement and hamstring dysfunction as a potential pain generator after ischial tuberosity apophyseal fracture non-union/malunion. Knee Surg Sports Traumatol Arthrosc. 2015 Oct 1. [Pubmed] [Google Scholar]


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