Injections for the different types of meniscus tears

Ross A. Hauser, MD., Danielle R. Steilen-Matias, MMS, PA-C

Non-surgical repair of the different types of meniscus tears

If you are reading this article you have likely been diagnosed with a meniscus tear and have just had, or are waiting for an MRI to determine the extent of your knee damage. Depending on your MRI results you will be offered one of three choices:

  1. Do nothing.
  2. Do something non-surgically.
  3. Get surgery.

The reason you are probably reading this article is that you are exploring all these options and are probably leaning towards finding another way besides surgery. In this article you are going to see a lot of research, the orthopedists will speak up, the physical therapists are going to speak up, and the regenerative therapist, health care providers offering regenerative medicine injections, that would be us, is going to speak up. So let’s look at the different types of meniscus tears and what you can do non-surgically to treat them.

We are going to present a brief video that explains the concept of knee instability and how it impacts your pain and function in a meniscus-damaged knee.

A brief video on knee instability and a bulging meniscus – the many types of meniscus tears may have ligament damage as a common factor

Non-Surgical treatment options for the different types of Meniscus tears

A December 2021 paper published in the Journal of experimental orthopaedics (1) revealed the thoughts of the attending members of the 2021 5th International Conference on Meniscus Science and Surgery in “for furthering the state of meniscus science in 2021.”

The most important findings of this survey were that the highest ranked future research and development focus areas should include meniscus repair, biologics, osteotomy procedures, addressing meniscus extrusion (your meniscus is sticking out beyond the shin bone and has its causes in root tear), and the development of new therapies for the prevention of Post-traumatic osteoarthritis. Currently, the reported most ‘valuable’ type of biologic for meniscus treatment was PRP, while amniotic fluid was reported as least ‘valuable’.

So what are we reading here? The doctors thought that the feature of meniscus tear treatment should be on:

Red zone tear, white zone tear. When non-surgical options can work and when surgery will be the “only” choice

We are now going to expand on our discussion of the White Zone Tear, the Red Zone Tear, and the tear that goes across the red zone and the white zone.

Menisci have two zones. The red zone is the meniscus’ outside zone the white zone is the inside zone. Meniscus tears are characterized by their placement within these two zones. In your many doctor visits, you probably received a pretty good education in what red zone tears and white zone tears are of the menisci.

A red zone tear lies within the blood-rich portion of the meniscus. Where there is a blood supply there is healing as blood brings the healing and growth factors needed for wound repair.

What are we seeing in this image?

If you have a red zone tear, there is a chance arthroscopic surgery can go in and sew it up. If you have a white zone tear, it is most likely that your meniscus will be removed. All or some of it. The great majority of meniscus arthroscopic surgeries are to REMOVE meniscus tissue. In this image, we note that the meniscus has a poor healing ability because approximately 70% of the meniscus gets no direct blood supply. This is why the meniscus has a white zone. In the other 30% of the meniscus that gets a blood supply, this creates the “red zone.”

If you have a red zone tear, there is a chance arthroscopic surgery can go in and sew it up. If you have a white zone tear, it is most likely that your meniscus will be removed. All or some of it. The great majority of meniscus arthroscopic surgeries are to REMOVE meniscus tissue.

If you have a red zone tear, there is a chance arthroscopic surgery can go in and sew it up. If you have a white zone tear, it is most likely that your meniscus will be removed. That would be all or some of it. The great majority of meniscus arthroscopic surgeries are to REMOVE some amount of meniscus tissue.

Partial-thickness tears or full-thickness tears: The other classification of the meniscus tear is related to the depth of the tear.

What are we seeing in this image?

Meniscus tears can be considered to either be partial-thickness tears or full-thickness tears. Partial-thickness tears are tears that only extend partway across the meniscus, while full-thickness tears extend fully across. So, if you have a full-thickness flap tear, then it is a tear that cuts across the meniscus completely.

Tears are considered to either be partial thickness tears or full thickness tears. Partial thickness tears are tears that only extend part way across the meniscus, while full thickness tears extend fully across. So, if you have a full thickness flap tear, then it is a tear that cuts across the meniscus completely.

No matter the tear, partial meniscectomy and physical therapy may not work or may work. It is hard to tell.

Above we cited a study from a group of physical therapists discussing how their patients perceived arthroscopic surgery and their (the patients) relative disappointment that they did not get surgery. The physical therapists wrote that these people need to be educated on the reality of the success of arthroscopic knee surgery.

This is a study from orthopedic surgeons writing in the medical journal Arthroscopy. (12) If ever there were to be a favorable study on the surgery you would think this was it. Not so. In this study, doctors suggest that there is currently no compelling evidence to support arthroscopic partial meniscectomy versus physical therapy. The studies evaluated in this research are not robust enough at this time to support claims of superiority for either alternative, and both arthroscopic partial meniscectomy or physical therapy could be considered reasonable treatment options for this condition.

They may work, one may or may not work better than the other. The research is not sure.

Two studies – seven years apart 2013 – 2020

We are going to look at two studies on physical therapy, surgical avoidance, and meniscus tears. Both lead by Jeffrey N. Katz, MD.  The first study, considered by many a landmark study, was published in the New England Journal of Medicine. (13)

Did the physical therapy group or the surgery group have more pain or less pain 5 years down the road?

Is successful meniscus surgery a matter of luck? Do you have the same chance for a successful outcome if you just rehab with exercise?

This is a March 2020 study published in the British Journal of Sports Medicine (15). What this study wanted to do was examine the ability of surgeons to predict the outcome of treatment for meniscal tears by arthroscopic partial meniscectomy and exercise therapy in middle-aged patients.

Here is how the study worked:

The surgeons of this study make a recommendation for treatment. Was surgery correct?

The point of this study is that the surgeons are looking at 20 patient profiles. The 20 people already had either surgery or exercise therapy. The results of how successful the surgery was and how successful the exercise therapy was, was used to determine if the surgeon made the “right call.”

Results: Surgeons making a successful meniscus surgery prediction and a coin toss. The chance was equal.

Typically when patients decide whether to have surgery or not they typically do not toss a coin. Probably some do because they do not have enough information to make a more educated assessment of their chances of having a successful surgery or having equal success with non-surgical options.

So here are the results of this study. Remember a surgeon was asked to look at 20 patient profiles and make a recommendation for surgery or no surgery. The 20 patients had already had surgery or exercise therapy and the successful results of their treatment had already been recorded. How did the surgeons do? They may as well have flipped a coin.

Here is what the study said:

Conclusions: Surgeons’ criteria for deciding that surgery was indicated did not pass the statistical examination. This was true regardless of a surgeon’s experience. These results suggest that non-surgical management is appropriate as first-line therapy in middle-aged patients with symptomatic non-obstructive meniscal tears.

In Comprehensive Prolotherapy, the knee joint instability is restored by repairing and regenerating tissue

We use non-surgical treatments for meniscus tears. We may use our Prolotherapy treatments and PRP. This is an in-office injection treatment. This video and the summary below is an introduction to our non-surgical treatments. It is presented by Danielle R. Steilen-Matias, MMS, PA-C.

Platelet Rich Plasma Therapy and Prolotherapy, which stimulates tendons, ligaments, and cartilage to heal, has many advantages over arthroscopy, which include:

Many patients at this point, exploring non-surgical options will look into stem cell therapy.

The reality of stem cell therapy

We don’t treat everyone with stem cell therapy

If you do not have a meniscus, stem cell therapy as an injection will not make a new one

Over expectation of what stem cell therapy can do may lead to patient disappointment


December 2021 the research on stem cell therapy for treating a meniscus

Here is a summary viewpoint of the current state of stem cell repair of a meniscus tear published in December 2021 in the journal Orthopaedic surgery.(10) According to the authors: “”Due to the special anatomical features of the meniscus, conservative or surgical treatment can hardly achieve complete physiological and histological repair. As a new method, stem cells promote meniscus regeneration in preclinical research and human preliminary research. We expect that, in the near future, in vivo injection of stem cells to promote meniscus repair can be used as a new treatment model in clinical treatment. The treatment of animal meniscus injury, and the clinical trial of human meniscus injury has begun preliminary exploration. As for the animal experiments, most models of meniscus injury are too simple, which can hardly simulate the complexity of actual meniscal tears, and since the follow-up often lasts for only 4-12 weeks, long-term results could not be observed. Lastly, animal models failed to simulate the actual stress environment faced by the meniscus, so it needs to be further studied if regenerated meniscus has similar anti-stress or anti-twist features.”

Still a great potential to repair

Despite these limitations, repair of the meniscus by MSCs has great potential in clinics. MSCs can differentiate into fibrous chondrocytes, which can possibly repair the meniscus and provide a new strategy for repairing meniscus injury.

If you are exploring stem cell therapy for a meniscus tear, the great likelihood that you are doing this research is that you are looking for an option for surgery. Please see our article Does stem cell therapy for knee meniscus tears and post-meniscectomy work?

Summary and contact us. Can we help you?

We hope you found this article informative and it helped answer many of the questions you may have surrounding your knee problems and knee instability.  If you would like to get more information specific to your challenges please email us: Get help and information from our Caring Medical staff

This is a picture of Ross Hauser, MD, Danielle Steilen-Matias, PA-C, Brian Hutcheson, DC. They treat people with non-surgical regenerative medicine injections.

Brian Hutcheson, DC | Ross Hauser, MD | Danielle Steilen-Matias, PA-C

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14 van de Graaf VA, Bloembergen CH, Willigenburg NW, Noorduyn JC, Saris DB, Harris IA, Poolman RW. Can even experienced orthopaedic surgeons predict who will benefit from surgery when patients present with degenerative meniscal tears? A survey of 194 orthopaedic surgeons who made 3880 predictions. British journal of sports medicine. 2020 Mar 1;54(6):354-9. [Google Scholar]
18 Dai TY, Pan ZY, Yin F. In Vivo Studies of Mesenchymal Stem Cells in the Treatment of Meniscus Injury. Orthopaedic Surgery. 2021 Nov 8.

This article was updated July 11, 2021



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