Medial Collateral Ligament Knee Injury

Your doctor or MRI tells you that you have a partial tear of the medial collateral ligament (MCL)  of the knee. What are your treatment options?

  • If your doctor reports that you have a Grade 1 MCL injury, it means that your ligament overextended, strecthed out a little too far, but did not tear.
  • If your doctor reports that you have a Grade 2 MCL injury, this means that a partial tear has occurred and you are probably feeling some type of instability, pain after prolonged periods of inactivity, your knee pain may wake you up at night.

For many athletes, after a few weeks, they can go about their training, game, running or cycling because the for most the best treatment was NOTHING – the injury should and did heal on its own. The MCL is a strong ligament and doctors have confirmed the resilience of the MCL in their published findings. What they noted, as many doctors who prefer to utilize non-surgical options, is that the most frequent MCL injury, near its femoral attachment can be healed spontaneously without surgical intervention.

A study from doctors at the Department of Orthopaedics, University of Toledo Medical Center in the  Journal of orthopaedics, (1) gives an introduction to the treatment problems of the knee’s medial collateral ligament:

  • Lesser injuries to the MCL can often be treated conservatively with early rehabilitation, but more significant tears often necessitate surgery. A thorough understanding of the MCL and associated injuries is essential for proper diagnosis and treatment.

It is fair to say that if you go into a surgeon’s office with a document MRI finding, the above is an accurate assessment of what you will hear. You may need a surgery, you may not. We will talk about the grade 3 MCL injury, a completely torn MCL below.

A partial MCL tear is capable of healing itself and even before complete healing occurs is sufficient enough to keep the knee stable

In incidence where the MCL is injured in isolation, Chinese university researchers writing in the Journal of engineering in medicine(2) found the healing characteristics of the MCL to be remarkable in their inconsistency, BUT, did find that the MCL could spontaneously heal. Listen to the researchers:

  • The medial collateral ligament (MCL) is one of the main ligaments that provide knee joint with major restraints against valgus (knees bending inwards), internal, and external torque (or twisting) loads. The MCL injury most frequently occurs near its femoral attachment (where it attaches to the thigh bone in the knee joint) but can be healed spontaneously.
  • Hence, the usual clinical treatment for MCL injury is conservative therapy with early controlled rehabilitation motion.
  • However, the effect of the variations in the healing conditions of the MCL portion (i.e. near the femoral insertion) is still unclear.

The purpose of this study was to observe how the MCL heals under different injury condition. That corresponded to:

  • early healing mechanisms in the MCL,
  • medium or middle stage healing mechanisms in the MCL,
  • and final (i.e. healthy) stages of the healing period.

What the researchers found was that at the medium or middle stage of healing, the MCK exhibited characteristics of a fully healed MCL.

  • What does this mean? A partial MCL tear is capable of healing itself and even before complete healing occurs is sufficient enough to do its job of maintaining knee stability
  • What does this mean? It means that a partial MCL tear, while it is healing on its own, may not be the cause of pain and instability and surgical treatment may interfere with healing and knee stability.

Does an MCL really heal on its own?

The answer is yes, the question is, what type of healing occurs? In a landmark study from 1983, which was most recently cited in two 2017 studies on MCL stability, doctors examined scar formation in MCL healing.

In this study in the American Journal of Sports Medicine(3) researchers studied injured MCLs in rabbits and discovered that true ligament healing does not occur. Rather, a ligament scar develops that is in many ways inferior to true ligament tissue. The researchers were curious about the healing of untreated ligaments: is there true ligament regeneration or is there scar healing only? How fast do these ligaments heal? Is healing complete when left untreated?

This study showed a number of things:

  • Untreated injured MCLs in the rabbit model did not have true ligament regeneration but rather formed a scar.
  • The scar tissue was chemically and mechanically abnormal in structure, showing changes in quality and quantity of collagen tissue.
  • The scar formation was slow but was a highly organized process of hemorrhaging, inflammation, proliferation and remodeling. Forty weeks after injury there were still changes taking place in the scar appearance.
  • The ligament scar tissue was mechanically inferior to normal ligament tissue and showed signs of plateauing or getting worse over time.
  • Researchers had reason to believe that the scar tissue would ultimately stretch out when placed under future stress.

The bottom line from this study is that ligaments heal by scar unless treated. Ligaments that heal with scar are significantly inferior in strength to normal ligaments and weak ligaments lead to ligament laxity, joint instability, and osteoarthritis.

MCL treatment options

Prolotherapy for MCL tears

The key to pain-free, healthy joints is healthy and strong ligaments and tendons. In the case of an injured MCL (or any injured ligament) is to treat it with Prolotherapy. Prolotherapy stimulates repair by inducing a mild inflammation in the weakened ligaments and tendons. The localized inflammation triggers a wound-healing cascade, resulting in the deposition of new collagen, the material that ligaments and tendons are made of. New collagen shrinks as it matures. The shrinking collagen tightens the ligament that was injected and makes it stronger. Prolotherapy has shown to be extremely effective at eliminating pain and sports injuries that are a result of ligament and/or tendon weakness. So instead of letting an injury “heal on its own” it’s best to treat injured ligaments with Prolotherapy to ensure proper regeneration of ligament tissue.

Prolotherapy helps provide whole knee healing environment and stabilization for the MCL injury

When patients experience an MCL injury, they typically also injure the other knee ligaments such as the anterior cruciate ligament (ACL) , posterior cruciate ligament (PCL), and Lateral Collateral Ligament (LCL). Traditional medicine likes to treat these types of injuries with surgery. Surgery, however, means cutting and removing. Cutting through important knee structures will eventually lead to more knee instability and degeneration of the knee joint.

Prolotherapy for an MCL injury involves injections inside the joint, to the MCL, and the surrounding affected tissues. This treatment is comprehensive in order to treat all of the weakened areas, as injury to the MCL often involves injury to the other ligaments and surrounding tissue of the knee joint.

Although a totally torn ligament usually requires surgery, Prolotherapy can play a key healing role here as well. First, because Prolotherapy has been shown to regenerate tissue, this treatment should be given a chance to help the ligament heal itself, even before surgery is considered. Secondly, Prolotherapy can also be a healing complement to surgery because the other ligaments around the knee, as well as the joint capsule itself, were at least stretched during the injury to the knee. Untreated, this stretching would most likely lead to instability of the knee joint.

Along with a controlled exercise program for healthy motion of the knee joint, Prolotherapy can successfully treat the injured medial collateral ligament and help patients get back to their normal activity levels.

Now let’s introduce another recent study on the effects of Prolotherapy injections on an MCL tear. A patient case study documents Prolotherapy treatment for a rugby player who had a grade 2 partial tear sprain of the MCL.

In his case, Prolotherapy, together with an exercise therapy program of three weeks had the patient pain free, with a full range of motion, and he was able to perform all rugby-specific movements.(4) The success of this study was in how fast the player was able to return – three weeks as s opposed to 4 to 8 weeks for a grade two sprain. Prolotherapy induced a quicker “spontaneous healing.”


Do you have a question about Medial Collateral Ligament Knee Injury? You can get help and information from our Caring Medical staff

1 Andrews K, Lu A, Mckean L, Ebraheim N. Medial collateral ligament injuries. Journal of orthopaedics. 2017 Dec 1;14(4):550-4. [Google Scholar]
Wan C, Hao Z, Wen S. The effect of healing in the medial collateral ligament of human knee joint: A three-dimensional finite element analysis. Proc Inst Mech Eng H. 2016 Jun 30. pii: 0954411916656662. [Google Scholar]
3 Frank C, Woo SL, Amiel D, Harwood F, Gomez M, Akeson W. (1983). Medial collateral ligament healing. A multidisciplinary assessment in rabbits. The Journal of Sports Medicine, 11(6). [Google Scholar]
4. Ada AM, Yavuz F. Treatment of a medial collateral ligament sprain using prolotherapy: a case study. Altern Ther Health Med. 2015 Jul;21(4):68-71. [Google Scholar]



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