Meniere’s Disease and Chronic cerebrospinal venous insufficiency
Ross Hauser, MD
We will often be contacted by people with a diagnosis of Meniere’s Disease. If you have this same diagnosis it is likely that you share the symptoms and conditions that these people tell us about. They have hearing loss, dizziness, vertigo, sensitivity to high-pitched sounds, lightheadedness, loss of balance, fatigue, swallowing difficulties, vision problems, and some people suggesting that they have an altered sense of reality or dissociation with reality. Some of these people have been suffering from Meniere’s Disease for years and even decades. Many also have tinnitus, inner ear pressure, and a lot of neck and shoulder pain.
Some will tell us that their Meniere’s Disease gets better when they have upper cervical spine chiropractic adjustments. They will also tell us that their chiropractors have noted a reverse curve in their cervical spine and vertebrae misalignment, especially C1-C2 Atlantoaxial instability. Others will tell us about their Idiopathic (no one knows where it is coming from) Intracranial Hypertension.
This article will concentrate on the aspects of Meniere’s Disease caused by upper cervical instability and the connection to Intracranial Hypertension and Chronic Cerebrospinal Venous Insufficiency.
Chronic cerebrospinal venous insufficiency and Meniere’s Disease
If you have made it to this article, you are likely someone who has been through a long medical history with Meniere’s Disease and are researching a bit deeper than simple facts about how many people are affected with Meniere’s Disease or that you have fluid in your ears possibly caused by various problems including autoimmune disease such as multiple sclerosis, allergy-causing Endolymphatic hydropsor or excessive build-up of the endolymph fluid in the inner ear, and/or a family history of Meniere’s disease. It is equally unlikely that at the onset of your Meniere’s Disease that anyone spoke to you about the connection to neck instability unless you brought up neck pain as part of your conditions to your doctors. Even then you were probably suggested to a change in diet and various hearing and balance tests and told that there is no cure for Meniere’s Disease but it could be managed by medication and change of lifestyle. Then you were told that in some people, Meniere’s disease will just go away or achieve spontaneous remission.
Again, in this article, we will discuss and focus on those aspects of upper cervical spine instability which may be the underlying cause of Meniere’s disease. Let’s being with a discussion of Chronic cerebrospinal venous insufficiency.
Chronic Cerebrospinal Venous Insufficiency is exactly what it sounds like. You have a chronic problem moving cerebrospinal fluid out of your brain via the venous or vein network. Since Meniere’s disease may be a condition caused by Multiple Sclerosis your doctor may have suggested you get a brain MRI to rule out MS. Once MS was ruled out and you had many of the coexisting conditions that were mentioned above along with your Meniere’s Disease, you and your doctor and perhaps your neurologist may be at a loss as to what may be causing the Meniere’s Disease and these other symptoms and conditions. Craniocervical Instability, upper cervical spine instability, cervical spine instability, and Multiple Sclerosis share the following challenges.
What are we seeing in this image? Chronic cerebrospinal venous insufficiency and how it may cause Meniere’s disease.
In this image, we are seeing the veins that make up the cervical venous system. The cervical venous system is part of the brain drainage system or glymphatic system. Fluids and waste products from the brain make their way out of the brain through this system. When these veins are compressed or impinged upon by the bones of the neck, the vertebrae, you can develop Chronic cerebrospinal venous insufficiency, your brain is not draining correctly. This can lead to conditions such as brain fog, memory problems, intracranial hypertension, pseudotumor cerebri (vision and headache problems) dizziness, head pressure, eye pain, and decreased or blurry vision, and as we will see in the research of this article Meniere’s Disease.
What are we seeing in this image? Arterial and venous obstruction of fluid into and out of the brain
I like to explain to patients this vital component of their brain health, the ability to flush out waste fluids from the brain and replace these fluids with fresh fluid, as the analogy of a Brain Toilet Obstruction. The feedback from our patients made it clear this analogy seemed to resonate with them as the best way to understand the fluid in and fluid out of “brain-draining.”
In this split image, the image to the left shows a stable neck with a normal cervical spine curvature. Everything is in the cervical spine in is its proper place. Cerebrospinal fluid drains and refills within the brain.
In the image to the right, we see cervical spine instability. The displacement of the C1 is exerting pressure on the arteries and veins leading into and out of the brain. The Cerebrospinal fluid is now backing up into the brain. In this situation, the fluid build up of Meniere’s Disease may occur.
The brain needs to drain out or flush out toxins and refill itself with fresh fluids. In the image to the right, it is pointed out that obstruction of the veins and arteries will cause a “clogged toilet.” What happens when the toilet clogs?
- The arteries that bring fresh oxygen, nutrients, and clean fluids to the brain will be impeded.
- The veins that help flush out toxic buildup will clog.
Research connecting Chronic cerebrospinal venous insufficiency and Meniere’s Disease
The researchers of a May 2017 study in the medical journal Acta Otolaryng (1) suggest and confirm a correlation between chronic cerebrospinal venous insufficiency (CCSVI) diagnosis and Meniere’s Disease. The researchers further suggest that chronic cerebrospinal venous insufficiency could be considered a new ultrasound vascular pattern of the cerebrospinal venous system in patients affected by definite Meniere’s Disease.
An August 2020 study in the medical journal Laryngoscope (2) evaluated the incidence of chronic cerebrospinal venous insufficiency in Meniere’s Disease patients and the effect of bilateral percutaneous transluminal (balloon) angioplasty of the jugular/azygos veins compared to medical therapy. Note: We do not offer angioplasty in our office, however, some patients may require this type of treatment. This study is presented here to show the connection between Meniere’s Disease and cerebrospinal venous insufficiency. Here are the learning points of this research:
- Five hundred fourteen subjects were included in the study, 412 affected by definite Meniere’s Disease, and 102 healthy controls.
- All patients underwent audiovestibular and vascular examination.
- Patients with Meniere’s Disease and concomitant cerebrospinal venous insufficiency were divided into two subgroups: patients who underwent vascular intervention with bilateral percutaneous transluminal angioplasty (PTA) of the jugular/azygos veins and patients treated with medical therapy (Medication).
Results: Over 80% of Meniere’s Disease patients had cerebrospinal venous insufficiency
- Chronic cerebrospinal venous insufficiency was diagnosed in 330/412 (80.1%) of the Meniere’s Disease patients.
- Conclusions: The results of the present study confirm the close relationship between vascular disorders and Meniere’s Disease. The encouraging responses to vascular interventional therapy on Meniere’s Disease symptoms suggest that this may be a promising path for interpretation and treatment of this complex disease.
Note: As explained previously, some people have blockage of the veins caused by vascular disease, some people have cerebrospinal venous insufficiency caused by cervical spine instability. We treat cervical spine instability.
In this video Ross Hauser, MD discusses general problems of ear pain, ear fullness, sound sensitivity, and hearing problems.
Atlantoaxial instability: C1 and C2 hypermobility causes cervical spine instability and artery, vein, and nerve compression
Above we saw how some people who have contacted our office report that their Meniere’s Disease gets better when they have upper cervical spine chiropractic adjustments. They will also tell us that their chiropractors have noted a reverse curve in their cervical spine and vertebrae misalignment, especially C1-C2 Atlantoaxial instability.
Atlantoaxial instability is the abnormal, excessive movement of the joint between the atlas (C1) and axis (C2). This junction is a unique junction in the cervical spine as the C1 and C2 are not shaped like cervical vertebrae. They are more flattened so as to serve as a platform to hold the head up. The bundle of ligaments that support this joint are strong bands that provide strength and stability while allowing the flexibility of head movement and allow unimpeded access (prevention of herniation or “pinch”) of blood vessels that travel through them to the brain.
In a 2015 paper appearing in the Journal of Prolotherapy, (3) our research team wrote that cervical ligament injury should be more widely viewed as the underlying pathophysiology (the cause of) atlantoaxial instability and the primary cause of cervical myelopathy (disease) including the problems I have written about in this article.
So here a connection may be made between weak and damaged cervical spine ligaments and the onset and progression of Meniere’s Disease. I would like to remind you, the reader, that Meniere’s Disease may have many causes, cervical spine instability from damaged cervical ligaments may be one cause.
The cervical ligaments are strong bands of tissues that attach one cervical vertebra to another. When the cervical spine ligaments are weakened, they cannot hold the cervical spine in proper alignment or in its proper anatomical curve. Your head begins to move in a destructive, degenerative manner on top of your neck. Treating and stabilizing the cervical ligaments can alleviate these problems by preventing excessive abnormal vertebrae movement, the development or advancing of cervical osteoarthritis, and the myriad of problematic symptoms they cause including nerve, vein, and arterial compression.
Summary and can we help you?
At the start of this article, we discussed how people could have problems with hearing loss, tinnitus, dizziness and vertigo, sensitivity to high pitched sounds, lightheadedness, loss of balance, fatigue, swallowing difficulties, vision problems, and some people suggesting that they have an altered sense of reality or dissociation with reality. Some of these people have been suffering from Meniere’s Disease for years and even decades. Many also have a lot of neck and shoulder pain.
In the above research, we have made the case that the complexity of your problems may be caused by cervical instability caused by weakened and damaged cervical spine ligaments. Now we will begin to make the case that your symptoms may be alleviated on a long-term more permanent basis with the use of Prolotherapy.
Prolotherapy is a regenerative injection technique that utilizes substances as simple as dextrose to repair and regenerate damaged ligaments.
In 2015, Caring Medical published findings in the European Journal of Preventive Medicine investigating the role of Prolotherapy in the reduction of pain and symptoms associated with increased cervical intervertebral motion, structural deformity, and irritation of nerve roots. We concluded that statistically significant reductions in pain and functionality, indicating the safety and viability of Prolotherapy for cervical spine instability. (3)
One of the most revealing tests we do in our office for upper cervical instability is a digital motion x-ray (DMX), which includes looking at how the C1 and C2 vertebrae align when tilting the head. In this video, Ross Hauser, MD shows an unstable and stable upper cervical digital motion x-ray.
How do I know if I’m a good candidate?
We hope you found this article informative and it helped answer many of the questions you may have surrounding the challenges that you may be facing with Meniere’s Disease. Just like you, we want to make sure you are a good fit for our clinic prior to accepting your case. While our mission is to help as many people with chronic pain as we can, sadly, we cannot accept all cases. We have a multi-step process so our team can really get to know you and your case to ensure that it sounds like you are a good fit for the unique testing and treatments that we offer here.
1 Attanasio G, Cagnoni L, Masci E, Ciciarello F, Diaferia F, Bruno A, Greco A, De Vincentiis M. Chronic cerebrospinal venous insufficiency as a cause of inner ear diseases. Acta oto-laryngologica. 2017 May 4;137(5):460-3. [Google Scholar]
2 Attanasio G, Califano L, Bruno A, Giugliano V, Ralli M, Martellucci S, Milella C, de Vincentiis M, Russo FY, Greco A. Chronic cerebrospinal venous insufficiency and menière’s disease: Interventional versus medical therapy. The Laryngoscope. 2020 Aug;130(8):2040-6. [Google Scholar]
3 Hauser RA, Steilen D, Gordin K. The Biology of Prolotherapy and Its Application in Clinical Cervical Spine Instability and Chronic Neck Pain: A Retrospective Study. European Journal of Preventive Medicine. 2015;3(4):85-102. [Google Scholar]