Caring Medical - Where the world comes for ProlotherapyPiriformis syndrome – can you get back to running?

Ross Hauser, MD  | Caring Medical Regenerative Medicine Clinics, Fort Myers, Florida
David N. Woznica, MD | Caring Medical Regenerative Medicine Clinics, Oak Park, Illinois
Katherine L. Worsnick, MPAS, PA-C  | Caring Medical Regenerative Medicine Clinics, Fort Myers, Florida
Danielle R. Steilen-Matias, MMS, PA-C | Caring Medical Regenerative Medicine Clinics, Oak Park, Illinois

Piriformis syndrome – can you get back to running?

We see many patients who are not really sure what is wrong with them, or, they are diagnosed with a problem that they do not really understand. Such is the case with Piriformis syndrome. For some, since lower back pain is a problem, a trip to the chiropractor was made. It is here that some of these patients were first made aware of Piriformis syndrome. In the chiropractor’s office, the patient may have been given an explanation that their problem is not one of a bulging or herniated disc pressing on a sciatic nerve, but it is the piriformis muscle that has entrapped the sciatic nerve and causing “herniated disc like symptoms.”

Having been given this explanation, the patient then seeks out a treatment plan. Hopefully they will find the one that works for them. In this article we will discuss various treatment pans including those we have been offering our patients for more than 26 years.

A typical Piriformis syndrome diagnosed patient

A typical Piriformis syndrome diagnosed patient we see is someone who exercises or works out a lot, or, competes in demanding levels of sport.

For this person their problems start sometimes suddenly as:

  • severe lower back pain,
  • pain in the hamstrings,
  • “tight thighs” or “tight glutes” or “weak glutes,”
  • significant or burning buttock pain
  • and sciatica like symptoms of burning, numbing pain radiating down one of both legs and even a sense of “numb toes.”

Many of these patient / athletes will tell us that they did try to work their way through these problems. They continued to run, swim and cycle, and managed the pain these activities were causing with anti-inflammatories, ice, massage and stretching. A foam roller is always in their sports kit.

Unfortunately, these treatments, they found, would sometimes make their problems worse. In fact some people had to eliminate all stretching exercises as they had become injury causing.

When all conservative treatments fail, a recommendation for an MRI or CAT scan to confirm that what this person needs is a surgery. A surgery that most patients do not want when they are told of the 4 month recovery time. This is when these people will contact our office seeking a surgical alternative and a treatment that will help them compete again.

Understanding piriformis syndrome, is it really a syndrome? What is this diagnosis? How can we treat this?

Piriformis syndrome is often overlooked as a cause of patient problems because it displays symptom similarities with other more diagnostically recognizable problems such as sciatica.

This is what a patient will explain to us and why their first treatments centered on sciatica pain management:

  • The patient went to the doctor concerned about a burning pain and numbness sensation in his/her buttocks, legs and feet. Often the pain woke them up in the middle of the night.
  • They decided to go to the doctor because his/her own pain management plan of aspirin, anti-inflammatories, heat, ice, yoga, stretching, resting and back braces have not helped. (Please refer to our article Why physical therapy and yoga did not help your low back pain.)
  • His/her problems have probably gone on for some time and symptoms are getting worse as you began to suffer from severe spasms in the lower leg and calf muscles.

Piriformis syndrome centers on the piriformis muscle as it rubs on the sciatic nerve causing irritation.

  • In Piriformis syndrome, like the sciatica symptoms we mentioned above, the pain can often travel down the back of the thigh and/or into the low back. Some patients will report spasms in addition to muscle pain in addition to tingling, and numbness in the butt, leg, and thighs.

Many times a patient will come in with an MRI that may show sciatic nerve and piriformis muscle abnormalities. However, because of the difficulty in making a piriformis syndrome diagnosis via MRI, the primary diagnosis is usually made following a physical examination.

Doctors describe the challenge of a correct diagnosis: For the patient a second opinion should be considered

Doctors writing in the European Journal of Orthopaedic surgery & traumatology (1) gave an updated assessment of the challenges of diagnosing piriformis syndrome as the true cause of a patient’s radiating pain.

The Sciatic notch of the lower back – By BodyParts3D is made by DBCLS – Polygondata is from BodyParts3D, CC BY-SA 2.1 jp, https://commons.wikimedia.org/w/index.php?curid=39311235

They write that Piriformis syndrome can be defined by a quartet of symptoms and signs. The most common symptoms reported were:

  • buttock pain,
  • pain aggravated on sitting,
  • external tenderness near the greater sciatic notch and
  • pain on any maneuver that increases piriformis muscle tension

They also warn that doctors should be aware that the simple straight leg raising test may not be adequate and more testing would need to be done to determine if Piriformis syndrome is the pain culprit or contributor to the patient’s pain.

They also agree that piriformis muscle pathology can cause sciatica as this has been clearly demonstrated.

Piriformis syndrome physical therapy and exercises – do they help or hurt?

When a patient visits the sports medicine physician, chiropractor, or other health care provider for treatment, it may be suggested to them that the symptoms and pain they are dealing with is being caused by the tight piriformis muscle. The patient and doctor would then work to loosen up the piriformis muscle, through exercises, manipulation, massage, and physical therapy.

Doctors at the Spinal Surgical Service, Weill Medical College of Cornell wrote in The Orthopedic clinics of North America (2) journal of the typical expectations of treatment a patient may receive. This will likely sound very familiar to you:

  • Physical therapy is the mainstay of conservative treatment of Piriformis muscle syndrome as it aims at stretching the muscle and reducing the vicious cycle of pain and spasm.
  • Physical therapy is usually enhanced by local cortisone injections or in some instances Botulinum toxin (Botox).
  • Surgery should be reserved as a last resort in case of failure of all conservative modalities.

For many of you reading this article, you have found that these treatments were not effective and you are facing the surgical recommendation, the “last resort.”

Yet other researchers agree with this treatment methodology. Writing in the journal Practical Neurology (3) doctors say: “owing to a lack of clinical trials and a lack of consensus on diagnosis, treatment of piriformis syndrome largely utilizes conservative methods, such as stretching, manual techniques, injections, NSAIDs, muscle relaxants, ice and activity modifications. The mainstay of treatment is piriformis stretching, which focuses on relaxing tight muscles to relieve nerve compression.”

Indeed, for some these treatments may be effective. If you are reading this article, it is probable that they were not effective for you.

Understanding treatment: The piriformis muscle does not just tighten up on its own

At Caring Medical, we look deeper into the cause of the problem. The piriformis muscle does not just tighten up on its own. We have found that in many patients with this condition a sacroiliac ligament injury or a hip ligament injury is the cause. Basically, the sacroiliac or hip ligaments are stretched out and loose. Consequently, when the piriformis muscle tries to contract, it can’t, so it starts to spasm. When the piriformis spasms, it pinches the sciatic nerve, which causes the pain, tingling, and numbness that the person experiences.

Trying to loosen the piriformis muscle is not going to work to alleviate the patient’s symptoms. For these patients, in our opinion, the symptoms of piriformis syndrome can only be alleviated by treating the underlying cause of the problem which is loose sacroiliac and/or hip ligaments.

In the Journal of Prolotherapy a case history of successful treatment with Prolotherapy is presented:

  • The patient is a long distance runner, who developed sacroiliac joint pain, iliotibial band problems, piriformis syndrome, patella femoral syndrome, and pain all along her entire right side.
  • The patient had sought extensive chiropractic and physiotherapy. Unfortunately, these treatments were all minimally successful at best, providing no real relief.

An acute episode occurred when during a run the patient “heard a crack, and felt searing pain through the inner thigh and groin.”

After visiting numerous doctors the patient was advised she had a “pulled groin muscle,” and to “stop running.” Since the patient was already experiencing extreme difficulties in simply walking, the doctor’s advice was of no help.

According to the patient: “Months of dedicated, daily physiotherapy treatments proved mostly futile until finally the physiotherapist, a marathoner herself, informed me of a treatment called Prolotherapy. She believed this would address the laxity of the ligaments of my right SI joint, which had culminated in what was in fact a fracture of the inferior pubis ramus resulting from multiple biomechanical problems, and laxity of the ligaments of the SI, exacerbated by many miles of running.”

Prolotherapy involves injections of dextrose, a simple sugar, into damaged ligaments. The treatment causes an inflammatory response which causes the growth of new and stronger ligaments. After the initial treatment the patient was informed to refrain from all vigorous activity for 48 hours as to not add any additional stress during that healing period, followed by no impact activities for two weeks.

The patient reported: “After two weeks of refraining from running, I gently eased back into my routine, seeing increased strength and decreased pain. Several months later, I had trained for and completed a half marathon, although with some SI pain. Another Prolotherapy treatment and several more months of smarter training, and I registered for, and completed the marathon that I had fractured out of and was sidelined from almost exactly one year earlier. Arguably, 42.2 kms of impact is about as good a test as you will find anywhere to demonstrate the efficacy of a treatment.

Figure 1. Michelle Murphy running the Detroit Marathon—something she thought would never be possible without the help of Prolotherapy.

In the two years since that pelvic fracture and subsequent Prolotherapy treatments, I have run four marathons, competed in numerous other road races of varying distances, as well as several triathlons. After a year of continuous training, I required one isolated Prolotherapy treatment for the same SI joint. Considering the amount of stress I have put on it with my running, if a minor tune up is called for in order to keep me moving and being an active participant in my own life, then so be it.”

Piriformis muscle syndrome is rarely a problem in isolation

When a patient comes in with a diagnosis of Piriformis muscle syndrome, we may also find that the patient may also suffer from signs and symptoms related to trochanteric bursitis  (please see our article Greater trochanteric pain syndrome – It is not sports related bursitis?) and weakness in the iliotibial band. (Please see our accompanying article Iliotibial band friction syndrome Knee pain in Runners.) These problems can also cause “sciatica.”

When examining the patient with Piriformis muscle syndrome, we may also We find weakness in the sacroiliac joint, hip joint, sacrotuberous and sacrospinous ligaments, trochanteric bursa, and iliotibial band/tensor fascia lata.

What is causing all these problems?

The sciatic nerve runs between the two heads of the piriformis muscle. When the piriformis muscle is spastic, the sciatic nerve may be pinched. Lumbosacral and hip joint weaknesses are two main causes of piriformis muscle spasm. Stretches and physical therapy directed at the piriformis muscle to reduce spasm help temporarily, but do not alleviate the real problem.

The iliotibial band/tensor fascia lata extends from the pelvis over the hip joint to the lateral knee. Its job is to help abduct the leg, especially during walking so the legs do not cross when walking.

When this band/muscle is tight, it puts a great strain on the sacroiliac and lumbosacral ligaments. Stretching this muscle is beneficial to many people with chronic hip/back problems. Stretching and massage feels good to people with chronically “tight IT bands.” Take this one step further though to understand why the bands/muscles become tight in the first place, which is joint instability generally in the hip or the knee. This instability needs to be properly identified and treated for the chronic tightness to be eliminated, along with the need to regularly stretch or massage the area in order to feel relief. Once the joint becomes stable, the continual tightness subsides.

Making sense of why treatment focused only on the Piriformis muscle is not helping you

Prolotherapy is the best treatment to help cause permanently strong tissue to form where a weakened sports injury exists. Prolotherapy stimulates the healing process and, therefore, decreases the length of time it takes for soft tissue sports injuries to heal. Prolotherapy, because it triggers the growth of normal collagen tissue, causes stronger ligaments and tendons to form. Consequently, the athlete returns to his or her game stronger. After Prolotherapy treatments, not only is the athlete able to return to the sport, but often the particular area that was injured will be stronger than before the injury and performance will be enhanced.

If you have questions about Piriformis muscle syndrome treatment, get help and information from our Caring Medical Staff

1 Hopayian K, Danielyan A. Four symptoms define the piriformis syndrome: an updated systematic review of its clinical features. European Journal of Orthopaedic Surgery & Traumatology. 2017 Aug 23:1-0. [Google Scholar]

2 Papadopoulos EC, Khan SN. Piriformis syndrome and low back pain: a new classification and review of the literature. Orthop Clin North Am. 2004 Jan;35(1):65-71. Review. [Google Scholar]

3. Norbury JW, Morris J, Warren KM, Schreiber AL, Faulk C, Moore DP, Mandel S, Mohnot D, Kalueff AV, DuRapau Jr VJ, Mohnot S. Diagnosis and management of piriformis syndrome. Pract Neurol. 2012 May:24-7. [Google Scholar]

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