Lumbar spinal stenosis surgery alternatives | Comprehensive Prolotherapy

David N. Woznica, MDDr. David Woznica Prolotherapist 

In this article, we will examine the challenges and findings of researchers looking for the optimal treatment for lumbar spinal stenosis.

Studies: No clear benefits were observed with surgery versus non-surgical treatment

Doctors at the Italian Scientific Spine Institute published their research in the Cochrane database of systematic reviews which gave this warning to patients considering surgery for spinal stenosis.

In the medical journal Current opinion in anaesthesiology, doctors discuss the latest trends in lumbar spinal stenosis treatments, this includes a run down of the conservative non-surgical treatments.

Here is what the researchers said: Our review of current literature within the past 12–24 months for the treatment of lumbar spinal stenosis serves to update providers on recent advances and comparisons regarding therapy spanning lifestyle modification, pharmacologic therapy, minimally invasive interventions, and surgical interventions.


Spinal Stenosis Infographic

In their study, surgeons from the Rothman Institute at Thomas Jefferson University wrote of the problem of correctly classifying patients with lumbar stenosis for the purpose of increasing effectiveness of treatments.

According to the researchers:

While surgery may be effective for some, the the surgical techniques vary widely from a decompression procedure to a spinal fusion procedure. This variation in technique and what the researchers call the “lack of an accepted classification system,” can lead to problems for patients with complications.(3)

We describe many spinal surgery techniques and their independent medical reviews in supportive research on this website including my articles:

What causes spinal stenosis and the “narrowing of the spine?”

Bone spurs form as a result of microinstability of the spine, as the body attempts to stabilize the unstable spine, which can eventually narrow the spinal canal and cause resultant spinal stenosis.

Spinal stenosis is defined as a specific type and amount of narrowing of the spinal canal, nerve root canals, or intervertebral foramina and can be either congenital or developmental or be acquired from degenerative changes.

Something has to be responsible for the back pain or leg pain in diagnosed cases of spinal stenosis. Most people will refer to some motion, often one of combined flexion and rotation that they performed before developing certain positional symptoms. For instance, symptoms that are worse with one position or motion (eg, walking or standing) then improve with spinal flexion (eg, sitting). This indicates that the spinal ligaments are loose and causing symptoms based on the patient’s position. This is why giving Comprehensive Prolotherapy to stabilize the ligaments is often the ideal treatment, even in patients who have been diagnosed with spinal stenosis.

In treating lumbar stenosis doctors are looking to alleviate pain from the nerves not ligaments

To quote from an article in the Journal of the American Academy of Orthopaedic Surgeons:

“Degenerative lumbar spinal stenosis is caused by mechanical factors and/or biochemical alterations within the intervertebral disc that lead to disc space collapse, facet joint hypertrophy, soft-tissue infolding, and osteophyte formation (bone overgrowth), which narrows the space available for the exiting nerve roots.

Nonsurgical management consists of pain medication and/or nonsteroidal anti-inflammatory drugs, physical therapy, and epidural steroid injections. If nonsurgical management is unsuccessful and neurologic decline persists or progresses, surgical treatment, most commonly laminectomy is indicated.”(4)

Surgical procedures for spinal stenosis: Here is new research on minimally invasive lumbar surgeries:

Nancy Epstein of Winthrop University Hospital wrote in the medical journal Surgical neurology international.

The incidence of nerve root injuries following any of the multiple MIS lumbar surgical techniques transforaminal lumbar interbody fusion (TLIF), posterior lumbarinterbody fusion (PLIF), anterior lumbar interbody fusions (ALIF), extreme lumbar interbody fusions (XLIF) resulted in more nerve root injuries when compared with open conventional lumbar surgical techniques

“Considering the majority of these procedures are unnecessarily being performed for degenerative disc disease alone, spine surgeons should be increasingly asked why they are offering these operations to their patients?”(5)

Types of Spinal Stenosis


Research findings warn doctors to stop doing certain spinal surgeries

Diagnosing stenosis as the cause of a patient’s pain is very problematic. We are going to the following problems that may lead to failed back surgery due to surgery not addressing the true cause of the patient’s pain.

There seems then to be confusion, if the patient is not complaining of back pain, but the MRI says it is stenosis, does the patient have a problem that needs to be operated on?

Published in the medical journal Osteoarthritis and Cartilage researchers in Japan discovered something unsettling for the diagnosed stenosis patient. It seems that many asymptomatic individuals (patients with no complaints or symptoms) have radiographic lumbar spinal stenosis.

So in 938 patients with an average age of about 66, they found when they did an MRI, Lumbar Spinal Stenosis was very prevalent. But when they asked the patient if they had back pain or other spinal problems, spinal stenosis complaint was uncommon.(6) See our article Failed Back Surgery Risk Factors | Too many inappropriate MRIs


More than 50% of the patients indicated that they would undergo spine surgery based on abnormalities found on MRI, even without symptoms”(7This according to research in the Journal of Neurosurgery

Add to this: In recent research, doctors in Mexico publishing in the Spanish language medical journal Cirugía y Cirujanos (Surgeons and surgery) say that spinal surgery failure for spinal stenosis patients is due mainly (61%) to surgical error and nearly 55% from misdiagnosis.(8)

The complexity of identifying lumbar stenosis from groin pain

In a paper from October 2017, Japanese researchers publishing in the medical journal Clinical neurology and neurosurgery looked to identify the prevalence of groin pain in patients with sacroiliac joint dysfunctionlumbar spinal canal stenosis, and lumbar disc herniation who did not have hip disorders.

They looked at:

Then they looked at

  1. corresponding spinal level of lumbar stenosis and lumbar disc herniation in the patients with groin pain;
  2. the pain areas in the buttocks and back; including pain increase while in positions such as sitting, lying supine, and side-lying; an sacroiliac joint dysfunction shear test (manual physical examination of range of motion); and four tender points composed of the posterior superior iliac spine (PSIS), long posterior sacroiliac ligament (LPSL), sacrotuberous ligament (STL), and iliac muscle. Please see our article on the role of ligaments in spinal instability and chronic back pain.


Conclusion: Doctors should be thorough in examining patients with stenosis reporting groin pain to find the true cause of the patient’s discomfort.(9)

Spinal Stenosis Injection Treatments

Patients receiving epidural steroid injections for lumbar spinal stenosis had less improvement and greater need for surgery

Researchers are very much like patients in that they assume a treatment that they are using is going to work to help patients with lumbar spinal stenosis. The same can be said for epidural steroid injections. Read our most recent article on the updated research on epidural steroid injections. These new studies agree with research published in the December 12, 2012 edition of Spine, suggesting the injections were associated with significantly less improvement at four years among all patients with spinal stenosis…Furthermore, epidural steroid injections were associated with longer duration of surgery and longer hospital stay. There was no improvement in outcome with ESI whether patients were treated surgically or nonsurgically.”(10)

Spinal Stenosis Prolotherapy

In comparison, Prolotherapy research in patients who failed traditional conservative management: Researchers in the UK explored the use of Prolotherapy in patients who had failed to respond to conservative approaches including spinal manipulation and physiotherapy. These patients had longstanding and often severe pain and disability. Utilizing only treatments that included 3 injections over a 3 to 5 week period, they confirmed that 91% of respondents were better or not worse off after 12 months.11

For some this concept of Prolotherapy helping spinal stenosis is difficult to grasp. Many patients cannot believe Prolotherapy will work when they have been convinced that drilling out more space is needed. Prolotherapy is not drilling.

We can think of spinal stenosis as two different disorders, one needs surgery and the other Prolotherapy. There is SSAR and SSWA which stand for Spinal Stenosis At Rest and then Spinal Stenosis With Activity. (See Figure)

Spinal Stenosis at Rest and with Movement

Surgery is needed for Spinal Stenosis At Rest but Prolotherapy resolves Spinal Stenosis With Activity. They are differentiated on symptoms and a test called electromyography/nerve conduction studies (EMG/ NCV). The patient who has severe pain, especially nerve irritation down the leg at rest has a narrowing off the space for the nerves that is not affected by activity. It means that there just is never enough room for the nerve, even at rest. In these instances, a lot of nerve damage or irritation is present on an EMG/NCV test. This patient would be referred for a surgical decompressive surgery, where the surgeon makes more room for the nerve. Any residual pain after the surgery can then be treated with Prolotherapy.

However, almost all the cases of spinal stenosis fall into the second category, Spinal Stenosis With Activity.

These are patients who have no symptoms when they are sitting and laying recumbent and resting. But upon standing or walking for too long, they develop back pain, buttock pain and pain down the leg. In other words, the symptoms are only precipitated with movement or change in position. This means that the nerves have enough room at rest, but the room for the nerve is decreased with standing or walking. The symptoms are dependent on position. Positional pain is a hallmark feature of conditions that respond to Prolotherapy, in the spine and any joint of the body!

Pinched nerve or lumbar radiculopathy

If you have ever experienced a pinched nerve or lumbar radiculopathy, you know the pain is excruciating. Burning pain zooming down an extremity can cause such blinding pain, it will stop anyone in their tracks. But even in cases of acute pain, we have to ask why this problem started in the first place. The answer is ligament laxity, which causes the vertebrae to slip out of place and pinch the nerve.

In our office, these cases are often seen as needing a two-part solution.

When presented with all this information, on a patient’s first visit, he/she is sometimes disbelieving that Prolotherapy or Prolotherapy in conjunction with Platelet Rich Plasma Therapy or Stem Cell Therapy can provide benefit and help relieve the pain of spinal stenosis, yet, the answer to their commonly asked questions can be found in the above research.

Research citations:

References for this article Lumbar stenosis and Prolotherapy

1 Zaina F, Tomkins-Lane C, Carragee E, Negrini S. Surgical versus non-surgical treatment for lumbar spinal stenosis. Cochrane Database Syst Rev. 2016 Jan 29;(1): [Google Scholar]

2 Patel J, Osburn I, Wanaselja A, Nobles R. Optimal treatment for lumbar spinal stenosis: an update. Current Opinion in Anesthesiology. 2017 Oct 1;30(5):598-603. [Google Scholar]

3 Schroeder GD, Kurd MF, Vaccaro AR. Lumbar Spinal Stenosis: How Is It Classified? J Am Acad Orthop Surg. 2016 Dec;24(12):843-852.  [Google Scholar]

4. Issack PS, Cunningham ME, Pumberger M, Hughes AP, Cammisa FP Jr. Degenerative lumbar spinal stenosis: evaluation and management. J Am Acad Orthop Surg. 2012;Aug;20(8):527-35.

5 Epstein NE. More nerve root injuries occur with minimally invasive lumbar surgery: Let's tell someone. Surg Neurol Int. 2016 Jan 25;7(Suppl 3):S96-S101.  [Google Scholar]

6. Ishimoto† Y, Noriko Y, Shigeyuki M, Hiroshi Y, et al. Associations between radiographic lumbar spinal stenosis and clinical symptoms in the general population: The Wakayama Spine Study. Osteoarthritis Cartilage. 2013 Mar 5. pii: S1063-4584(13)00706-1. doi: 10.1016/j.joca.2013.02.656.  [Google Scholar]

7. Franz EW, Bentley JN, Yee PP, Chang KW, Kendall-Thomas J, Park P, Yang LJ. Patient misconceptions concerning lumbar spondylosis diagnosis and treatment. J Neurosurg Spine. 2015 May;22(5):496-502. doi: 10.3171/2014.10.SPINE14537. [Google Scholar]

8. Romero-Vargas S, Obil-Chavarria C, Zárate-Kalfopolus B, Rosales-Olivares LM, Alpizar-Aguirre A, Reyes-Sánchez AA. [Profile of the patient with lumbar failed surgery syndrome at National Institute of Rehabilitation. Comparative analysis]. Cir Cir. 2015 May 15.  [Google Scholar]

9. Kurosawa D, Murakami E, Aizawa T. Groin pain associated with sacroiliac joint dysfunction and lumbar disorders. Clinical Neurology and Neurosurgery. 2017 Aug 30.  [Google Scholar]

10. Radcliff K, Kepler C, Hilibrand A, Rihn J, Zhao W, Lurie J, Tosteson T, Albert T, Weinstein J. Epidural Steroid Injections Are Associated with Less Improvement in the Treatment of Lumbar Spinal Stenosis: A subgroup analysis of the SPORT. Spine (Phila Pa 1976). 2012 Dec 12.  [Google Scholar]

11. Jacks A, Barling T. Lumbosacral prolotherapy: a before-and-after study in an NHS setting. International Musculoskeletal Medicine. 2012 Apr 1;34(1):7-12.  [Google Scholar]

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