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This article will cover information on Prolotherapy including general questions on Prolotherapy treatments, side effects, research, reviews, and medical studies.

Ross Hauser, MD

Prolotherapy is an in-office injection treatment that research and medical studies have shown to be an effective, trustworthy, reliable alternative to surgical and non-effective conservative care treatments. In our opinion, based on extensive research and clinical results, Prolotherapy is superior to many other treatments in relieving the problems of chronic joint and spine pain and, most importantly, in getting people back to a happy and active lifestyle. This is why it is the Caring Medical treatment method of choice.

• In our clinics, we offer our method of Prolotherapy. We call this method H3 Prolotherapy. We consider it the evolution of the traditional Hackett-Hemwall type Prolotherapy into Hackett-Hemwall-Hauser Prolotherapy.  The Hauser Prolotherapy technique has developed over 27 years of continual service. For those of you first exploring the treatment and not sure what these names are or mean, consider H3 Prolotherapy as the evolution of Prolotherapy protocols based on 80 years of research and clinical observation and based on tens of thousands of treatments.

While we treat with H3 Prolotherapy methods we will refer to these treatments simply as Prolotherapy for the remainder of this article.

Is Prolotherapy like cortisone? 

• The difference between Prolotherapy and Cortisone is extensive.
• Cortisone when injected into the joint can successfully mask pain. Many people have very successful treatments with Cortisone. We typically see patients who have a long history of Cortisone injection and these injections are no longer effective for them.
• Cortisone has been shown, in many studies, to accelerate degenerative osteoarthritis through cartilage breakdown.(1)
• Over the years we have seen many patients who have received corticosteroid (cortisone) injections for joint pain. Unfortunately for many, excessive cortisone treatments lead to a worsening of chronic pain. Again, while some people do benefit from cortisone in the short-term – the evidence however points to cortisone causing more problems than it helps.

Prolotherapy is a regenerative injection treatment used to treat joint and spine pain by repairing damaged and weakened ligaments and tendons.

• Prolotherapy is considered a viable alternative to surgery, and as an option to pain medications, cortisone and other steroidal injections.
• The Prolotherapy procedure is considered a safe, affordable option that allows the patient to keep working and/or training during treatment.
• H3 Prolotherapy difference: It is typically best to treat all or most of the ligaments of an unstable joint if that joint or its surrounding structures are painful. Multiple joints and structures can be treated with each visit.

What is the evidence for Prolotherapy?

For patients who are looking into Prolotherapy, please understand that this is a specialty procedure with technique and experience being a key component. What we present on our website is based on our experience and research and does not apply to all practitioners or injection therapies.

In July 2016, our doctors at Caring Medical published findings on the effectiveness of Prolotherapy treatments in the medical journal: Clinical Insights: Arthritis and Musculoskeletal Disorders, here are the summary highlights:

Our doctors reviewed 32 studies on dextrose prolotherapy for chronic musculoskeletal pain. The following conclusions are made:

• Prolotherapy is supported in the treatment of tendinopathies in patients who fail conservative therapies;
• Prolotherapy is supported in the treatment of knee osteoarthritis
• Prolotherapy is supported in the treatment of finger joint osteoarthritis in patients who do not respond to conservative therapies;
• Prolotherapy is supported in the treatment of back pain and
• Prolotherapy is supported in the treatment of pelvic pain in patients who fail to respond to conservative therapies. .  .

Overall, Prolotherapy has been demonstrated to be efficacious and should be considered as a treatment for pain and dysfunction associated with chronic musculoskeletal conditions, particularly tendinopathies and osteoarthritis.

Hauser RA, Lackner JB, Steilen-Matias D, Harris DK. A Systematic Review of Dextrose Prolotherapy for Chronic Musculoskeletal Pain. Clinical Medicine Insights Arthritis and Musculoskeletal Disorders. [Google Scholar]

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Prolotherapy for Knee Pain

In this video, Ross Hauser, MD explains a Prolotherapy knee treatment as performed at our Caring Medical clinics. This is not typical of the way treatment may be performed in other doctor’s offices.

Video learning and demonstrated points:

• Prolotherapy is an injection technique that stimulates growth factor cells that work to repair damaged joints.
• Prolotherapy can be very helpful in patients with knee instability or hypermobility caused by damaged knee ligaments and tendons. Knee instability is a cause of knee osteoarthritis and degenerative wear and tear.
• In this video, Ross Hauser, MD is seen demonstrating intra-articular (inside the knee) as well as injections surrounding the outside of the knee.
• In addition to knee osteoarthritis, Prolotherapy injections can help patients with problems that will eventually lead to degenerative knee disease.
• Patellofemoral pain syndrome and patellofemoral tracking problems.
• Weakened and damaged ligaments and tendons and their attachments to the bones and muscles that make the knee work.
• In the video you see that Dr. Hauser is injecting into the:
  • The knee’s medial joint line, at the medial collateral ligament location
  • The pes anserine tendon
  • The medial patellar retinaculum tendon
  • The distal quadriceps attachments
  • The lateral joint line where the lateral collateral ligament is located
  • The attachment of the iliotibial band
  • The capsular knee ligament attachments

Published research papers from our doctors at Caring Medical on Knee Disorders

• Prolotherapy knee cartilage regeneration: Standard Clinical X-ray Studies Document Cartilage Regeneration in Five Degenerated Knees
  • This paper was published in the Journal of Prolotherapy.
  • Hauser R, Cukla J. Standard Clinical X-ray Studies Document Cartilage Regeneration in Five Degenerated Knees After Prolotherapy. Journal of Prolotherapy. 2009;1(1):22-28. [Google Scholar]
• Outcomes of Prolotherapy in Chondromalacia Patella Patients: Improvements in Pain Level and Function
  • This paper was published in the journal Clinical medicine insights. Arthritis and musculoskeletal disorders.
  • Hauser RA, Sprague IS. Outcomes of prolotherapy in chondromalacia patella patients: improvements in pain level and function. Clin Med Insights Arthritis Musculoskelet Disord. 2014 Feb 17;7:13-20. doi: 10.4137/CMAMD.S13098. PMID: 24596471; PMCID: PMC3937178. [Google Scholar] [Pubmed]
• Prolotherapy as an Alternative Treatment for Osteochondritis Dissecans: Two Cases of Young Baseball Players
  • Hauser RA. Prolotherapy as an Alternative Treatment for Osteochondritis Dissecans: Two Cases of Young Baseball Players. Journal of Prolotherapy. 2011;3(1):568-71. [Google Scholar]
• Bone Marrow Prolotherapy for Degenerative Joint Disease
  • This paper was published in the journal Clinical medicine insights. Arthritis and musculoskeletal disorders.
  • Hauser RA, Orlofsky A. Regenerative injection therapy with whole bone marrow aspirate for degenerative joint disease: a case series. Clin Med Insights Arthritis Musculoskelet Disord. 2013 Sep 4;6:65-72. doi: 10.4137/CMAMD.S10951. PMID: 24046512; PMCID: PMC3771705.  [Google Scholar] [Pubmed]
• A Retrospective Study on Dextrose Prolotherapy for Unresolved Knee Pain at an Outpatient Charity Clinic in Rural Illinois
  • This paper was published in the Journal of Prolotherapy.
  • Hauser RA, Hauser MA. A retrospective study on dextrose Prolotherapy for unresolved knee pain at an outpatient charity clinic in rural Illinois. Journal of Prolotherapy. 2009;1(1):11-21. [Google Scholar]
• Platelet Rich Plasma Prolotherapy as First-line Treatment for Meniscal Pathology
  • This paper was published in the medical journal Practical Pain Management
  • Hauser RA, Phillips HJ, Maddela H. Platelet rich plasma Prolotherapy as first-line treatment for meniscal pathology. Pract Pain Manag. 2010 Jul;10(6):53-64. [Google Scholar]

Recent Prolotherapy knee research

A May 2020 study in the Annals of Family Medicine made this simple statement at the conclusion of the research findings:

“Intra-articular dextrose prolotherapy injections reduced pain, improved function and quality of life in patients with knee osteoarthritis compared with blinded saline injections. The procedure is straightforward and safe; the adherence and satisfaction were high.”

Shan Sit RW, Keung Wu RW, Rabago D, et al. Efficacy of Intra-Articular Hypertonic Dextrose (Prolotherapy) for Knee Osteoarthritis: A Randomized Controlled Trial. Ann Fam Med. 2020;18(3):235‐242. doi:10.1370/afm.2520 [Google Scholar]

Another study from May 2020 published in The Journal of Alternative and Complementary Medicine made these observations: “These findings suggest that dextrose prolotherapy is effective at reducing pain and improving the functional status and quality of life in patients with knee osteoarthritis.

Sert AT, Sen EI, Esmaeilzadeh S, Ozcan E. The Effects of Dextrose Prolotherapy in Symptomatic Knee Osteoarthritis: A Randomized Controlled Study. J Altern Complement Med. 2020;26(5):409‐417. doi:10.1089/acm.2019.0335 [Google Scholar]

In January 2019, David Rabago, MD, of the University of Wisconsin School of Medicine and Public Health, published research on Dextrose Prolotherapy for Symptomatic Knee Osteoarthritis in the Journal of Alternative and Complementary Medicine. The study concluded “(suggested) that Prolotherapy in this primary care clinic is feasible and acceptable.” In other words, it is beneficial to patients.

Rabago D, Kansariwala I, Marshall D, Nourani B, Stiffler-Joachim M, Heiderscheit B. Dextrose Prolotherapy for Symptomatic Knee Osteoarthritis: Feasibility, Acceptability, and Patient-Oriented Outcomes in a Pilot-Level Quality Improvement Project. The Journal of Alternative and Complementary Medicine. 2019 Jan 28. [Google Scholar]

Articles for patients looking for options for eventual knee replacement

• The evidence for Prolotherapy Injections for knee osteoarthritis
• Stem Cell Prolotherapy for knee cartilage regeneration
• Knee cartilage surgery and knee cartilage non-surgical repair
• Bone Marrow Aspirate Prolotherapy for knee pain
• How fast can I return to work after knee replacement? 15 to 30% of patients do not return to work
• I am an active 75 year old who does not want a knee replacement.
• Chronic knee swelling
• My doctor says my knee should not hurt me as much as it does.
• Bone loss before the knee replacement
• Should You Explore Alternatives to Knee Replacement Surgery?

Chronic knee problems from an active lifestyle, physically demanding work, or sports-related knee injuries

• Treating osteoarthritis in the aging athlete
• Chronic Knee Pain, Knee Instability, and Degenerative Knee Disease

Meniscus tears

• Prolotherapy for Meniscus Tears
• The evidence for non-surgical bucket handle meniscus tear repair

Patella / Knee Cap

• Surgery and non-surgical treatments for acute and chronic knee cap dislocation
• Patellar Tendinopathy | Jumper’s Knee
• Treating Chondromalacia Patella – Patellofemoral Pain Syndrome

Knee Ligaments

• ACL reconstruction surgery alternatives and treatment options | Prolotherapy, PRP and stem cells
• After ACL Reconstruction, Complications and post-surgery knee instability treatments
• Medial Collateral Ligament Knee Injury
• LCL | Lateral Collateral Ligament Injury of the Knee
• Posterior Cruciate Ligament (PCL) Injury and Treatments

Knee diagnosis

• Treating loose bodies in your knee
• Iliotibial band friction syndrome Knee pain in Runners
• Knee Tendinopathy | Tendinosis | Tendonitis
• Osgood-Schlatter Disease
• Baker’s cyst treatment – Prolotherapy Injections

Meniscus

• The many types of meniscus tears
• Prolotherapy for Meniscus Tears

Pain AFTER knee arthroscopic surgery

• Research: For many, arthroscopic knee surgery does not work and in fact may be harmful
• Knee cartilage surgery and knee cartilage non-surgical repair

Pain AFTER knee replacement

• Who can and who can’t kneel after knee replacement
• Finding help for post knee replacement pain

Prolotherapy and PRP (Platelet Rich Plasma) Injections for Knee Pain

Comprehensive Prolotherapy is an injection technique utilizing many healing factors. They can include or be used in conjunction with Dextrose, Blood Platelets, and stem cells. The stem cells and blood platelets are drawn from you the patient. We typically DO NOT offer stem cell therapy for knee pain as a first option. We may offer PRP treatments in conjunction with Prolotherapy at initial treatment visits.

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WE OFFER PRP with PROLOTHERAPY. We do not offer PRP as a single injection treatment.

In this video, Ross Hauser, MD explains how one injection of PRP will likely not work

• We will often get emails from people who had previous PRP therapy without the desired healing effects.
• We explain to these people that their treatment probably did not work because the single PRP injection was not enough treatment to resolve their problem of degenerative knee damage, various tears, and their knee instability. The PRP may have tried to create a patch in the meniscus or the cartilage or address a tendon tear, but the instability and the wear and tear grinding that tears at the knee remained.

Articles:

• Platelet rich plasma injections for meniscus tears
• Platelet Rich Plasma for Knee Osteoarthritis When it works When it will not work and When is it better than other treatments

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Prolotherapy and Stem Cell Therapy for Knee Pain

Bone marrow derived stem cells

We do not offer stem cell therapy to every patient, in fact we offer this treatment very rarely. The treatment is usually offered only in the most advanced cases of knee degenerative disease. The articles below give a comprehensive review of when stem cell therapy will work, when it will not work, and the realistic options of when it should be considered.

• Stem Cell Prolotherapy for knee cartilage regeneration
• Do stem cell injections for knee meniscus tears and post-meniscectomy work?
• Can you repair a bone-on-bone knee without stem cell therapy?
• Why stem cell therapy did not or will not work for your knee pain?
• Bone Marrow Aspirate Prolotherapy for knee pain

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Prolotherapy for Back Pain

Published research papers from our doctors at Caring Medical on low back pain

• Dextrose Prolotherapy for Unresolved Low Back Pain: A Retrospective Case Series Study
  • This paper was published in the Journal of Prolotherapy.
  • Hauser RA, Hauser MA. Dextrose prolotherapy for unresolved low back pain: a retrospective case series study. Journal of Prolotherapy. 2009;3:145-55.[Google Scholar]

Caring Medical patients are often surprised to learn that Prolotherapy can heal most disc problems in the neck and back. While we talk about Prolotherapy healing joint pain that results from ligament and tendon injuries, most people are unaware that disc problems result from ligament injuries or instability along the spine. Patients with degenerative disc disease, herniated discs, bulging discs, bone on bone, etc can all be healed with Prolotherapy.

Prolotherapy works to stabilize the ligaments of the spine allowing discs to get back into position and can even create space for a person who has lost space due to one or more degenerated discs. In Prolotherapy research from the doctors of Caring Medical, patients with more than four years of unresolved low back pain were shown to have had their pain improved, stiffness, range of motion, and quality of life measures even 12 months subsequent to their last Prolotherapy session.

Back pain by an initial diagnosis

• Non-surgical treatment options for lumbar spinal stenosis
• Sacroiliac Joint Dysfunction Treatments – What can help you, what may not
• Sciatica and lumbar radiculopathy Prolotherapy treatments
• The evidence for an alternative to Spinal fusion surgery – Spinal ligament repair injections,
• Prolotherapy non-surgical treatment of a bulging or herniated disc
• Minimally invasive spinal surgery procedures for various back problems
• Facet Joint Osteoarthritis. New research says it is caused by spinal ligament weakness

Spondylolisthesis,  Spondylolysis, Spondylisis

• Spondylolisthesis,  Spondylolysis, Spondylisis. A problem of disc degeneration or ligament degeneration?
• Low Back Pain in female high school athletes lumbar spondylosis

Failed back surgery syndrome

• Failed Back Surgery Syndrome treatment options – the new research
• Failed Back Surgery Syndrome. Was your MRI even accurate?
• How does a woman go in for spinal fusion surgery and come home with pelvic pain?
• Post-laminectomy syndrome

Conservative Care Back Pain Options

• Why physical therapy and yoga did not help your low back pain
• Alternatives to Epidural Steroid Injections – Why do patients still get epidurals?

 

Prolotherapy for Shoulder Pain

Ross Hauser, MD explains and demonstrates a Prolotherapy treatment to the shoulder.

• This particular person is not sedated. The treatment is well tolerated. The treatment begins at 1:36.
• The first injection was intra-articular, directly into the shoulder joint.
• Next the acromioclavicular joint. Shoulder osteoarthritis, rotator cuff tendon issues including tears as well as tendinosis, responds well to Prolotherapy.
• Next are the posterior shoulder structures including the posterior joint capsule as well as the various ligament attachments in the back of the shoulder.
• Next the interior structures in the front of the shoulder are done including the ligaments as well as the various rotator cuff tendon attachments including the Supraspinatus tendon.
• Prolotherapy is effective for rotator cuff tears, labral tears and biceps tendonitis, various tendonitis as well as shoulder instability.
• Finally treating the acromioclavicular joint, or AC joint as the biceps tendon attachments.

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Published research papers from our doctors at Caring Medical on Shoulder Disorders

• Prolotherapy: A Non-Invasive Approach to Lesions of the Glenoid Labrum; A Non-Controlled Questionnaire Based Study
  • This paper was published in The Open Rehabilitation Journal.
  • Hauser RA, Dolan E, Orlofsky A. Prolotherapy: a non-invasive approach to lesions of the glenoid labrum; a non-controlled questionnaire-based study. The Open Rehabilitation Journal. 2013 Dec 27;6(1).[Google Scholar]
• A Retrospective Study on Hackett-Hemwall Dextrose Prolotherapy for Chronic Shoulder Pain at an Outpatient Charity Clinic in Rural Illinois
  • This paper was published in the Journal of Prolotherapy.
  • Hauser RA, Hauser MA. A retrospective study on Hackett-Hemwall dextrose prolotherapy for chronic shoulder pain at an outpatient charity clinic in rural Illinois. J Prolotherapy. 2009;4:205-16. [Google Scholar]

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Articles

• Repairing a SLAP tear without surgery

Rotator Cuff Tears

• Rotator Cuff Tendinopathy Comparing Prolotherapy, PRP and Cortisone
• Partial rotator cuff tear – Do you really need a surgery?
• Alternative to Rotator Cuff Tear Surgery – The evidence for non-surgical options

Shoulder Instability

• Can I avoid shoulder replacement surgery? The evidence for shoulder replacement alternatives
• Chronic shoulder dislocation, subluxation and shoulder instability
• Shoulder impingement syndrome – Surgeons tell patients say no to surgery – What are your options?
• Treating bone spurs in the shoulder is difficult
• Swimmer’s shoulder treatment – subacromial shoulder pain
• Shoulder Adhesive Capsulitis – Frozen Shoulder Treatment

In this video, a general demonstration of Prolotherapy and PRP treatment is given for a patient with repeated shoulder dislocations

Danielle R. Steilen-Matias, MMS, PA-C narrates the video and is the practitioner giving the treatment:

• PRP or Platelet Rich Plasma treatment takes your blood, like going for a blood test, and re-introduces the concentrated blood platelets and growth and healing factors from your blood into the shoulder. The treatment is explained further below.
• In the shoulder treatment, I treat all aspects of the shoulder including the ligament and tendon injections to cover the whole shoulder.
• The patient in this video is not sedated in any way. Most patients tolerate the injections very well. The treatment goes quickly. However, we do make all patients comfortable including sedation if needed.
• This patient in particular comes to us with a history of repeated shoulder dislocations. His MRI findings showed multiple labral tears and rotator cuff problems.
• The patient complained of shoulder instability typical of the ligament and tendon damage multiple dislocations can do.
• With the patient laying down, treatment continues to the anterior or front of the shoulder. The rotator cuff insertions, the anterior joint capsule and the glenohumeral ligaments are treated.
• PRP is introduced into the treatment and injected into the front of the shoulder. PRP is a form of Prolotherapy where we take concentrate cells and platelets from the patient’s blood and inject that back into the joint. It is a more aggressive form of Prolotherapy and we typically use it for someone that has had a labral tear, shoulder osteoarthritis, and cartilage lesions.
• PRP is injected into the shoulder joint and the remaining solution is injected into the surrounding ligaments in this case it was in his anterior shoulder attachments to address the chronic dislocations.

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Prolotherapy for Cervical Spine Instability and related symptoms

This section will also provide information on the following symptoms as they relate to neck pain and cervical spine instability

• Headache and Migraine
• TMJ
• Whiplash Associated Disorder
• Hearing problems
• Vision problems
• Swallowing difficulties
• Dizziness
• Drop Attacks
• Vagus Nerve disorders

Since 1993, Ross Hauser, MD and Marion Hauser, MS, RD have developed Caring Medical Regenerative Medicine Clinics into one of the world’s leading clinics for Prolotherapy (including dextrose, PRP, and stem cells) with a commitment to helping the toughest chronic pain cases. ​Today, our work is heavily focused on the cervical spine.

Published research papers from our doctors at Caring Medical on Cervical Spine Instability and related symptoms

• Chronic Neck Pain: Making the Connection Between Capsular Ligament Laxity and Cervical Instability
  • This paper was published in the European Journal of Preventive Medicine
  • Steilen D, Hauser R, Woldin B, Sawyer S. Chronic neck pain: making the connection between capsular ligament laxity and cervical instability. The Open Orthopaedics Journal. 2014;8:326-345. [Google Scholar]
• The Biology of Prolotherapy and Its Application in Clinical Cervical Spine Instability and Chronic Neck Pain: A Retrospective Study
  • This paper was published in the European Journal of Preventive Medicine
  • Ross Hauser, MD, Steilen-Matias D, Gordin K. The biology of prolotherapy and its application in clinical cervical spine instability and chronic neck pain: a retrospective study. European Journal of Preventive Medicine. 2015;3(4):85-102. [Google Scholar]
• Non-Operative Treatment of Cervical Radiculopathy: A Three Part Article from the Approach of a Physiatrist, Chiropractor, and Physical Therapists
  • This paper was published in the Journal of Prolotherapy
  • Ross Hauser, MD, Batson G, Ferrigno C. Non-operative treatment of cervical radiculopathy: a three part article from the approach of a physiatrist, chiropractor, and physical therapists. Journal of Prolotherapy. 2009;1(4):217-231.
• Dextrose Prolotherapy for Unresolved Neck Pain
  • This paper was published in Practical Pain Management
  • Hauser R, Hauser M, Blakemore K. Dextrose prolotherapy for unresolved neck pain. Practical Pain Management. 2007;7(8):58-69.
• Cervical Instability as a Cause of Barré-Liéou Syndrome and Definitive Treatment with Prolotherapy: A Case Series
  • This paper was published in the European Journal of Preventive Medicine
  • Hauser R, Steilen-Matias D, Sprague IS. Cervical instability as a cause of Barré-Liéou syndrome and definitive treatment with prolotherapy: a case series. European Journal of Preventive Medicine. 2015;3(5):155-166. [Google Scholar]

Degenerative Disc Disease in the Cervical Spine

• Treatment of Cervical Spondylosis
• Cervical neck instability | Regenerative medicine and Prolotherapy for chronic neck pain

Cervical Spine instability and Whiplash Associated Disorders and Post Concussion Syndrome

• Treatment of Whiplash associated disorders
• Prolotherapy treatments for chronic neck pain after an automobile accident | Case review of three patients
• Do I have Post-concussion syndrome? Or do I NOT have Post-concussion syndrome?

Cervical Spine instability and TMJ

• The evidence for TMJ injections into the jaw and cervical spine

Cervical Spine instability and hearing problems

• Tinnitus is a symptom of cervical spine instability

Cervical Spine instability and vision problems

• Chronic Neck Pain and Blurred or Double Vision Problems – Is the answer in the neck ligaments?

Cervical Spine instability and headaches

• Occipital neuralgia and Suboccipital headache – C2 neuralgia treatments without nerve block or surgery
• Vestibular migraine and spontaneous vertigo – Migraine Associated Vertigo
• Cervicogenic headaches – Migraines, tension headaches and cervical neck instability
• Cluster headache treatment – cervical ligament instability and the trigeminal and vagus nerves
• Neurogenic and Nonspecific-type thoracic outlet syndrome – Diagnosis and treatment

Ross Hauser, MD. Cause of occipital neuralgia and migraines as seen on DMX and resolved with Prolotherapy

In this video, Ross Hauser, MD offers a brief introduction to causes of occipital neuralgia and migraines and treated with the aid of DMX (Digital Motion X-Ray and simple dextrose Prolotherapy cervical spine injections.

Cervical spine instability and symptoms of dizziness, fainting, drop attacks, and other neurological symptoms

• Vertebrobasilar insufficiency. Every time I turn my head I get dizzy. Sometimes I almost pass out.
• Cervical Vertigo and Cervicogenic Dizziness
• Heart racing, heart rate variability, and high blood pressure. A cervical spine problem?
• How cervical spine instability pinches on arteries and disrupts, impedes, and retards blood flow into the brain.
• Cervical dystonia and spasmodic torticollis treatment
• Cervical disc disease and difficulty swallowing – cervicogenic dysphagia
• Can Chronic fatigue syndrome and Myalgic encephalomyelitis be caused by cervical stenosis and cervical spine instability?
• The evidence cervical neck problems can cause urinary incontinence
• Neck-Tongue Syndrome treated with Prolotherapy

Cervical spine fusion surgery

• Cervical artificial disc replacement
• The evidence for non-surgical cervical radiculopathy treatments
• Atlantoaxial instability treatment and repair without surgery
• Anterior Cervical Discectomy and Fusion – Before and after
• Patients report problems with sexual function after cervical spine surgery

Prolotherapy for hip pain

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Published research papers from our doctors at Caring Medical on Shoulder Disorders

• Regenerative Injection Therapy (Prolotherapy) for Hip Labrum Lesions: Rationale and Retrospective Study
  • This paper was published in The Open Rehabilitation Journal.
  • Hauser R, Orlofsky A. Regenerative injection therapy (prolotherapy) for hip labrum lesions: rationale and retrospective study. The Open Rehabilitation Journal. 2013 Oct 18;6(1). [Google Scholar]

In the Journal of Prolotherapy, we sought to show how Prolotherapy could provide high levels of patient outcome satisfaction while avoiding hip surgery. Here is what we reported:

• We examined Sixty-one patients, representing 94 hips, who had been in pain an average of 63 months We treated these patients quarterly with Hackett-Hemwall dextrose Prolotherapy.
• This included a subset of 20 patients who were told by their medical doctor(s) that there were no other treatment options for their pain and a subset of eight patients who were told by their doctor(s) that surgery was their only option.

Patients were contacted an average of 19 months following their last Prolotherapy session and asked questions regarding their levels of pain, physical and psychological symptoms and activities of daily living, before and after their last Prolotherapy treatment.

Results: In these 94 hips,

• pain levels decreased from 7.0 to 2.4 after Prolotherapy;
• 89% experienced more than 50% of pain relief with Prolotherapy;
• more than 84% showed improvements in walking and exercise ability, anxiety, depression and overall disability;
• 54% were able to completely stop taking pain medications.

The results confirm that Prolotherapy is a treatment that should be highly considered for people suffering from chronic hip pain.

Published research on Prolotherapy:

Dr. Ross Hauser and our team have published a number of research papers, case studies, and scientific editorials in the Journal of Prolotherapy, including articles on Prolotherapy as an alternative to surgery; Prolotherapy for chronic back pain; cartilage regeneration in knees; Stem cell therapy for degenerative joint disease; Prolotherapy as for meniscus tears, and many, many more.

Our Prolotherapy research papers, case studies, & scientific editorials:

• Articular Cartilage Regeneration
• Avascular Necrosis Case Report
• Big Toe and Bunion Pain
• Bone Marrow Prolotherapy for Degenerative Joint Disease
• Cartilage Degeneration with NSAIDs
• Chronic Ankle Pain
• Chronic Hip Pain
• Complex Regional Pain Syndrome
• Consensus Statement on Prolotherapy for Musculoskeletal Pain
• Corticosteroid Injections
• Dextrose Prolotherapy for Musculoskeletal Pain
• Prolotherapy for Headache and Migraine Pain
• Direct Bone Marrow Aspirate Therapy
• Elbow Pain
• Foot & Toe Pain
• Hand & Finger Pain
• Hip Labrum Lesions
• Joint Hypermobility Syndrome
• Joint Instability Treatment with Prolotherapy
• Ligament Injury and Healing
• Morton’s Neuroma Pain
• Osteoarthritis Pain: Can Prolotherapy Help?
• Osteochondritis Dissecans
• Over-manipulation Syndrome
• PRP Injection Technique
• Prolotherapy as an Alternative to Surgery
• Rationale for Direct Bone Marrow Aspirate
• Systematic Review of Dextrose Prolotherapy
• Thumb Arthritis
• TMJ Dysfunction Pain
• Upper Cervical Instability
• Wrist Pain

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1 https://scholar.google.com/scholar?cluster=3169869242871934775&hl=en&as_sdt=0,31

1 Hauser RA. The deterioration of articular cartilage in osteoarthritis by corticosteroid injections. Journal of Prolotherapy. 2009;2:107-23. [Google Scholar]

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