Your bad diet and weight is destroying your knees and will send you to a nursing home

Marion Hauser, MS, RD

One of the most obvious ways to help a patient with degenerative knee pain and metabolic syndrome (abdominal obesity, hypertension, and diabetes) is to help them understand that a healthy lifestyle can be extraordinarily beneficial to their joint pain, especially knees and spines.

One of the hardest things to convince a patient of is that they need to examine their food choices and lifestyle choices and make immediate and meaningful changes to help try to save their knee or to help with their back pain.

It is very likely that if you are reading this article, you have:

You also have moderate to severe knee and/or back pain and are losing your mobility and ability to work or function. Your adult children may be talking to you about considering assisted living one day in the future. Why? Because you are having difficulty moving and you may be on the verge of “Locomotion Syndrome.”

Your inability to move pain-free, without frailty and instability is related to body mass index

Your inability to move pain-free, without frailty and instability, is called “Locomotion Syndrome.” There are some obvious causes of “Locomotion Syndrome.” These include progressive degenerative disorders such as degenerative joint disease, hip osteoarthritis, knee osteoarthritis, degenerative diseases of the ankle and foot, and osteoporosis. Obviously disorders that would make it very difficult for someone to walk. But what if you did not have a significantly degenerated spine and joint disease and you have problems walking, or maintaining your balance, or even standing? What else could it be?

Let’s look at a November 2019 study in the medical journal Geriatrics & Gerontology International (1) that looks at aging patients to see what is causing aging patients their locomotion problems. The researchers state: The objective of the present study was to identify the factors related to onset and progression of Locomotion Syndrome in the absence of degenerative joint and spine disorders.

So they gathered and examined 1034 volunteers (444 men, 590 women, average age 63.5 years).

They divided the volunteers into two groups:

Then the grouped these people by age, sex, body mass index, muscle strength, gait ability, pain, body balance, spinal sagittal alignment, geriatric syndrome (locomotive syndrome, frailty and sarcopenia or bone loss) and Quality of Life scores.

The somewhat obvious findings were in patients without degenerative disease.

A look at Locomotive Syndrome – reduced mobility requiring nursing care

In January 2019, researchers at Nara Medical University in Japan published a study in the journal Modern Rheumatology (2). What they wanted to observe and assess was the impact of musculoskeletal diseases, depressive mental state, and hypertension on locomotive syndrome.

Learning points of this research:

In November 2018 another Japanese research team lead by Tokai University Oiso Hospital researchers looked at people with reduced muscle strength to measure the relationship with muscle frailty and metabolic syndrome leading to locomotive syndrome and required nursing care. This was published in the Journal of Orthopaedic Science.(3)

A problem for women

Here are the leaning points of this study:

Abdominal obesity, hypertension, and diabetes accelerates knee pain and osteoarthritis and Locomotion Syndrome

In October 2018, researchers in the journal Clinical Rheumatology (4) reinforced these findings.

The goal of the study was to take patients who had metabolic syndrome (abdominal obesity, hypertension, and diabetes), and knee osteoarthritis and examine the patient’s clinical history, functional capabilities, and match that with scans and MRIs of their knees.

The obvious conclusion? You will probably walk a lot better and feel a lot better if the issues of Abdominal obesity, hypertension, and diabetes are confronted.

If you have a big belly. Look down. You are looking at an inflammation processing plant. Your fat cells are pumping out inflammation to your joints

Dr. Karel Pavelka of the Czech Republic has published findings in the Fall 2017 issue of the Czech language journal Internal Medicine. (5) Here are his bullet points:

In other words, your fat cells are pumping out inflammation.

The message again: Your fat cells are pumping out inflammation

State Medical University researchers in Russia (6) have published their observations on 164 patients with osteoarthritis. Eighty-two patients were diagnosed with Metabolic Syndrome, Eighty-two were not and used as controls.

In the 82 patients with Metabolic Syndrome, clear indications of the negative impact of the disorder were seen:

Doctors in France cited these same findings in their research on factors affecting joint healing and metabolic syndrome in Current Opinion in Rheumatology: (7)

In other words -abdominal obesity, hypertension, and diabetes are destroying your joints as if it were a wear and tear disease.

Research: Your big belly is causing your joint swelling

University researchers in Australia write in the journal PLoS One (Public Library of Science one) (8) of the established risks obesity plays in osteoarthritis.

The researchers fed Wistar rats a high-carbohydrate, high-fat diet for a period of 8 and 16 weeks. The study showed that obesity-induced by this diet is associated with spontaneous and local inflammation of the synovial membranes in the rats even before the cartilage degradation.

This was followed by increased synovitis and increased macrophage infiltration (immune cells are now invading the areas causing swelling and edema) into the synovium and a predominant elevation of pro-inflammatory M1 macrophages (A specific type of immune cell).

This study demonstrates a strong association between obesity and a dynamic immune response locally within synovial tissues before cartilage degradation.

The problems of managing insulin

Doctors writing in the journal Medical Hypotheses (9) offered evidence making a connection between insulin, inflammation, and joint pain here are the bullet points of their findings.

Reducing circulation insulin levels can be achieved in many cases with health-professional guided lifestyle and dietary changes.

Eating foods that maximize healing

The same researching team cited above also examined the recent advances in the knowledge of osteoarthritis and its association with obesity and metabolic syndrome through systemic mechanisms.

Type 2 diabetes has been described in two (studies) as an independent risk factor for osteoarthritis.” In these animal studies, diabetic rodents display spontaneous and more severe osteoarthritis than their non-diabetic counterparts.

The negative impact of diabetes on joints could be explained by the induction of oxidative stress and pro-inflammatory cytokines (systemic low-grade inflammation) and by joint tissues exposed to chronic high glucose concentration.

The message here is simple: Abdominal obesity, hypertension, and diabetes = knee pain and accelerated knee osteoarthritis. The choice to do something about it is yours.

If you have questions about metabolic syndrome and osteoarthritis joint pain, get help and information from our Caring Medical staff

1 Imagama S, Ando K, Kobayashi K, Machino M, Tanaka S, Morozumi M, Kanbara S, Ito S, Inoue T, Seki T, Ishizuka S. Multivariate analysis of factors related to the absence of musculoskeletal degenerative disease in middle‐aged and older people. Geriatrics & Gerontology International. 2019 Nov 1;19(11):1141-6. [Google Scholar]
2 Akahane M, Maeyashiki A, Tanaka Y, Imamura T. The impact of musculoskeletal diseases on the presence of locomotive syndrome. Modern rheumatology. 2019 Jan 2;29(1):151-6. [Google Scholar]
3 Mitani G, Nakamura Y, Miura T, Harada Y, Sato M, Watanabe M. Evaluation of the association between locomotive syndrome and metabolic syndrome. Journal of Orthopaedic Science. 2018 Nov 1;23(6):1056-62. [Google Scholar]
4 Abd EL, Shaat RM, Gharbia OM, Boghdadi YE, Eshmawy MM, El-Emam OA. Osteoarthritis of knee joint in metabolic syndrome. Clinical rheumatology. 2018 Jul 23:1-7. [Google Scholar]
5 Pavelka K. [Osteoarthritis as part of metabolic syndrome?] Vnitr Lek. 2017 Fall;63(10):707-711. [Google Scholar]
6 Vasilyeva LV, Lakhin DI. Clinical features of osteoarthritis in patients with metabolic syndrome. Terapevticheskii arkhiv. 2017;89(5):65. [Google Scholar]
7 Courties A, Sellam J, Berenbaum F. Metabolic syndrome-associated osteoarthritis. Curr Opin Rheumatol. 2017 Mar;29(2):214-222. [Google Scholar]
8 Sun AR, Panchal SK, Friis T, Sekar S, Crawford R, Brown L, Xiao Y, Prasadam I. Obesity-associated metabolic syndrome spontaneously induces infiltration of pro-inflammatory macrophage in synovium and promotes osteoarthritis. PLoS One. 2017 Aug 31;12(8):e0183693. doi: 10.1371/journal.pone.0183693. eCollection 2017. [Google Scholar]
9 Askari A, Ehrampoush E, Homayounfar R, Bahramali E, Farjam M. Serum insulin in pathogenesis and treatment of osteoarthritis. Med Hypotheses. 2017 Feb;99:45-46. [Google Scholar]



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