Shoulder replacement complications
Ross A. Hauser, MD., Danielle R. Steilen-Matias, PA-C.
Many patients have excellent outcomes following shoulder replacement surgery. Some people do not have success and have resulting complications. This article will review some of the more recent research surrounding complications.
People have very successful shoulder replacements, some doctors suggest, however, shoulder replacement surgery may make things worse. How do you know who you are?
Complications from shoulder replacement surgery are a risk factor of the surgery. That is well understood and has concerned doctors for many years. Back in 2015, researchers from Texas Orthopedic Hospital, the University of Houston, University of Texas, (1) noted great increases in the number of shoulder replacements being performed and that with more shoulder replacements being done, more shoulder replacement revision surgeries with be needed to address complications from the first surgery.
- In this paper 21.6% of patients followed post-surgery (8 out of 37 patients) required a second surgery for postoperative complications.
- Overall, 54% of patients (20 out of 37) suffered from intra- or postoperative complications.
The paper concluded that shoulder replacement improved function in many patients, but with a high rate of complications and reoperations.
That was then. In 8 years since the same complication rates and concerns exist.
The list of shoulder replacement complications – pain after shoulder replacement.
An October 2019 study (2) outlined to radiologists what they needed to look for in an MRI and x-rays of patients complaining of pain after shoulder replacement. The research came from the Angers University Hospital in France and was published in the European Society of Radiology’s journal Insights Into Imaging.
- Shoulder arthroplasties are divided into three categories: reverse shoulder arthroplasty, total shoulder arthroplasty, and partial shoulder joint replacement (including humeral hemiarthroplasty and humeral head resurfacing arthroplasty).
- Each of these prostheses can present complications, either shared by all types of replacement or specific to each. The complications included:
- Periprosthetic fractures
- Humeral component loosening
- Heterotopic ossification
- Implant failure, and nerve injury.
- Specific to reverse shoulder replacement implantation:
- Scapular notching
- Acromial fractures
- Specific complications of total shoulder replacement:
- Glenoid component loosening.
- Rotator cuff tear
- Side note reference: A February 2023 German paper (3) explained glenoid loosening, including protrusion (the prosthetic part of the replacement has loosened and is now sticking out), rotator cuff insufficiency, including instability, and early/late infection as primary concerns. These concerns can be addressed by replacing the bone of the glenoid socket defects but can still include post-operative complications including dislocation, component loosening, and infection. They do note: “Revision of anatomical to reverse arthroplasty shows better clinical outcomes and lower complication rates than anatomical revision.”
- Specific to partial shoulder joint replacement:
- Progressive wear of the native glenoid.
- Each of these prostheses can present complications, either shared by all types of replacement or specific to each. The complications included:
The authors noted: “Knowledge of (these) different types of shoulder (replacement implants) prostheses and their complications’ radiological signs are crucial for the radiologist to initiate prompt and adequate management.” In other words, the above provides a list to radiologists looking for the source of pain following a shoulder replacement.
Shoulder replacement works better for older patients…but complications, and painkiller use, are still a concern to surgeons
Here are the bullet points to recent medical studies:
- Doctors in the United Kingdom write in the medical journal Shoulder and Elbow that the management of glenoid bone loss is a major challenge in both complex primary and revision arthroplasty surgery. (4)
- Doctors writing in The Journal of Bone and Joint Surgery noted that shoulder surgery was seen as a further complication of rotator cuff disease. “Secondary rotator cuff dysfunction is a recognized complication following shoulder arthroplasty. We hypothesized that the rate of secondary rotator cuff dysfunction would increase with follow-up and result in less satisfactory clinical and radiographic outcomes.” (5)
- A February 2020 (6) update from the Hospital for Special Surgery journal offered this:
- A total of 824 cases of revision shoulder arthroplasty were found. Eighty-seven patients (10.5%) had infections prior to revision and 133 patients (16.1%) had dislocations prior to revision. . .The most common complication of revision shoulder arthroplasty was found to be surgical site infection, affecting 10.9% of patients. In the time period studied, 89 patients underwent more than one revision shoulder arthroplasty.”
People have failed shoulder surgeries and researchers say: “no adequate explanation in the literature” can provide a reasonable explanation why.
Now let’s look at a University of Copenhagen paper published in June 2022 (7). Here the study team found: “worse outcomes for patients with previous surgery for instability independent of age, sex, and arthroplasty (the type of shoulder surgery, whether it was shoulder resurfacing or shoulder replacement, reverse or traditional) type. The reason cannot be deduced from our study and there is no adequate explanation in the literature. Several factors could, in theory, have an adverse effect on the outcome for these patients. A long history of instability and previous surgery may lead to eccentric glenoid wear and subsequently a technically demanding operation with risk of persisting instability, subluxation of the humeral component, or loosening of the glenoid component.”
Soft tissue damage after shoulder replacement, a leading cause of surgery failure
In September 2019, a paper in the Clinics in Orthopedic Surgery (8) noted that “The majority of patients with shoulder instability after anatomic shoulder arthroplasty (replacement) have both soft tissue imbalance and component malposition. Rotator cuff (surgical) repair after shoulder replacement has also had a poor success rate. Additionally, revision surgery with anatomic components and soft tissue reconstruction has had a high failure rate. Consequently, both instability and symptomatic rotator cuff dysfunction after anatomic shoulder arthroplasty are preferably treated with revision to a reverse prosthesis.” In common terms, Reverse shoulder surgery.
Obesity is a complication concern in shoulder replacement
- Doctors at the University of Alabama at Birmingham found that patients suffering from Metabolic syndrome, that is large waistlines (obesity), high triglyceride levels, high cholesterol, high blood pressure, and high cholesterol, are associated with considerable complication risk before, during, and after shoulder replacement surgery. (9)
Doctors from the Mayo Clinic writing in the Journal of Bone and Joint Surgery discuss the problems of obesity caused in patients after shoulder replacement surgery.
Here is what they said:
- Increasing Body Mass Index (Obesity) was associated with an increased risk of the need for a second or revision surgical procedure, reoperation, revision for mechanical failure, and superficial infection.
- Increased BMI was also associated with an increased risk of revision for mechanical failure.
- The most marked association between increasing BMI and any complication in shoulder arthroplasty was its association with superficial wound infection.
- It is important to consider these findings when counseling patients, estimating risks and estimating complication risks in policy decisions. (10)
Malnutrition, obesity, and anemia
A January 2022 study published in the Journal of Shoulder and Elbow Surgery (11) added to this by suggesting: “Malnutrition, obesity, and anemia contribute to significantly higher costs after shoulder arthroplasty. Medical strategies to optimize patients before shoulder arthroplasty are warranted to reduce total 90-day encounter charges, length of stay, and risk of readmission within 90 days of surgery. Optimizing patient health before shoulder surgery will positively impact outcomes and cost containment for patients, institutions, and payors after shoulder arthroplasty.”
Obese patients do get benefits
Another January 2022 study published in the Journal of Shoulder and Elbow Surgery (12) suggested: “Both non-obese and obese patients can expect clinically significant improvements in pain, motion, and functional outcome scores following (shoulder and reverse shoulder replacement). Obese patients reported significantly more postoperative pain, lower outcome scores, and less ROM compared with non-obese patients after both (shoulder and reverse shoulder replacement) at an average follow-up of 5 years.”
Understanding the reverse total shoulder replacement and conventional shoulder replacement surgery.
When conventional total shoulder replacement is judged not to be effective, a reverse total shoulder replacement may be suggested as an option.
The procedure sounds exactly as it is named. In a traditional shoulder replacement, a plastic “cup” is fitted into the shoulder socket (glenoid), and a metal “ball” is attached to the top of the upper arm bone (humerus). In a reverse total shoulder replacement, the socket and metal ball are switched.
The benefits of the reverse procedure are studied in a paper published in the medical journal Orthopedics. (13)
- The paper suggests that a reverse total shoulder arthroplasty is better suited for older patients with glenohumeral arthritis and a deficient rotator cuff.
- However, as a semi-constrained prosthesis, (that is implants that create artificial stability by limiting the prosthesis range of motion) a conventional reverse total shoulder replacement in a young patient could fail over time because of the polyethylene wear and subsequent osteolysis – the joint replacement causes accelerated bone loss.
Postoperative outcomes are disappointing, and the complication rate is high
- The researchers in the current study suggest at first that a metal-on-metal prosthesis may avoid this type of failure. However, they concluded: “Although metal-on-metal total shoulder replacement may appear to be an attractive choice in the treatment of young patients with limited reconstructive options, postoperative outcomes are disappointing, and the complication rate is high.”
Another study from Dr. Pascal Boileau of the Department of Orthopedic and Sports Surgery Pasteur 2 Hospital, University Institute of Locomotion and Sports in France examined outcomes and complications in young patients undergoing revision reverse total shoulder arthroplasty (RTSA) for failed prior total shoulder arthroplasty or ball replacement and compared them with those of older patients undergoing the same procedure.
- While reverse total shoulder arthroplasty is effective in reducing pain and improving function after failed arthroplasty in young patients, complication rates are high and expectations should be managed appropriately. Subjective outcome scores are worse for older patients. (14)
German orthopedic surgeons noted in their January 2023 paper (15) that “current data show a mean complication rate for reverse shoulder replacement of around 4%. The most common complications are instability, infection, component loosening, and periprosthetic fracture. . . Also, “Revision surgery for reverse shoulder replacement is challenging, and an individual treatment plan is necessary.”
Complications leading to re-operation are often multiple and underestimated
- Shoulder replacement infection: In another study, doctors say that one of the greatest risk factors for infection after shoulder replacement was a history of prior failed shoulder surgery. So replacing the shoulder in an attempt to fix the first shoulder surgery had a high risk of infection.
Back to the study from Dr. Boileau: The most common causes of revision surgery after reverse total shoulder arthroplasty (RTSA) are:
- prosthetic instability (38%),
- infection (22%),
- humeral problems (21%) including loosening, unscrewing, and fracture,
- and, lastly, problems of polyethylene glenoid loosening (13%). (14)
Complication challenges some patients face after reverse shoulder replacement
A March 2021 paper in the journal Clinics in Shoulder and Elbow (16) lists the complication challenges some patients face after reverse shoulder replacement. Here is what these researchers wrote:
“Reverse shoulder arthroplasty is an ideal treatment for glenohumeral dysfunction due to cuff tear arthropathy (degenerative disease). As the number of patients treated with reverse shoulder arthroplasty is increasing, the incidence of complications after this procedure also is increasing.
The rate of complications in reverse shoulder arthroplasty was reported to be 15%-24%.
Recently, the following complications have been reported in order of frequency:
- periprosthetic infection,
- periprosthetic fracture,
- neurologic injury,
- scapular notching (a wearing away of the scapular)
- acromion or scapular spine fracture,
- and aseptic loosening of the prosthesis.
However, the overall complication rate has varied across studies because of different prostheses used, improvement of implant and surgical skills, and different definitions of complications.”
Overuse or “radical use of reverse total shoulder replacement in patients without rotator cuff deficiency may cause more harm than good.
When considering a shoulder replacement, many people are given the choice or are suggested one or another type of shoulder replacement. An August 2022 study in the journal Medicine (17),
“Reverse total shoulder replacement, which was originally designed mainly for irreparable rotator cuff damage, has gained popularity in recent years for the treatment of advanced shoulder osteoarthritis instead of the clinically standard total shoulder replacement. However, this Reverse total shoulder replacement has some nonnegligible flaws such as higher complication rates and economic cost (this means that the patient required much more medical services), not to mention the following problems caused by irreversible physical structural damage. Therefore, the employment of reverse total shoulder replacement needs to be carefully considered.”
What the researchers did in this study was to compare reverse total shoulder replacement with standard total shoulder replacement in osteoarthritis patients with or without rotator cuff damage. The focus being on rotator cuff damage and recommendations that could help surgeons in their clinical decision-making process.
What the researchers noted was that they believed the overuse of “radical use of reverse total shoulder replacement in patients without rotator cuff deficiency may cause more harm than good. The researchers then assessed the medical records of 57,156 shoulder replacement patients. Patients were divided into 2 groups according to the presence of rotator cuff deficiency.
- Reverse total shoulder replacement patients in the rotator cuff deficiency group had significantly higher transfusion rates and longer hospital stays.
- Reverse total shoulder replacement patients without rotator cuff deficiency had a statistically significantly higher number of implant-related mechanical complications, acute upper respiratory infections, and postoperative pain.
- Overall, reverse total shoulder replacement incurred higher costs in both groups.
- For osteoarthritis patients with rotator cuff deficiencies, Reverse total shoulder replacement has its benefits as complication rates were comparable to total shoulder replacement. For those patients without rotator cuff deficiencies, the use of reverse total shoulder replacement should be reconsidered as there were more complications with higher severity.
Why was the patient sent to a revision shoulder replacement? What were the revision surgery complication rates?
An August 2021 study comes to us from the Brighton and Sussex Medical School and the University Hospitals Sussex and Dorset in the United Kingdom. It was published in the journal Bone & joint open. (18)
The researchers of this paper told their fellow physicians that “it is important to understand the rate of complications associated with the increasing burden of revision shoulder arthroplasty (replacement). Currently, this has not been well quantified. This review aims to address that deficiency (lack of understanding of what is causing the complications and what can realistically be done about it) with a focus on complication and reoperation rates, shoulder outcome scores, and comparison of anatomical and reverse prostheses (should you get the anatomically correct shoulder replacement of the reverse shoulder replacement) when used in revision surgery.”
Why was the patient sent to a revision shoulder replacement? According to the researchers, the indications for revision include:
- Component loosening 20% (601/3,041 patients),
- Shoulder instability 19% (577/3,041 patients),
- Rotator cuff failure 17% (528/3,041 patients), and
- infection 16% (490/3,041 patients).
The complications after the revision shoulder replacement were recorded as:
- Intraoperative complication (a complication that arose during the revision surgery, during surgery) was 8% (this was measured as 230 shoulder complications out of 2,915 patients in the study).
- Postoperative complication was 22% (825 of 3,843 patients in the study).
- Reoperation rates were 13% (584 of 3,843 patients in the study).
The researchers then left us with these take-home messages:
- Revision to reverse total shoulder arthroplasty is associated with better outcomes than revision to anatomical total shoulder arthroplasty (better to have a reverse shoulder replacement the second time around).
- Intraoperative complication rate was 8%, postoperative complications rate was 22%, and reoperation rate was 13% following revision shoulder arthroplasty. (Revision shoulder surgery has a high complication rate).
- Outcomes from revision shoulder arthroplasty show clinically important improvement in patient-reported outcome measures. (Many people got great benefits from the revision shoulder replacement).
- Revision to reverse geometry total shoulder replacement rather than to anatomical total shoulder replacement from any index (primary procedure whether reverse or anatomically correct shoulder replacement) procedure appears to result in lower complication rates and better postoperative outcome scores.
The realistic assessment of revision total shoulder replacement. The revision surgery is a high risk, if it works out the patient is better off. If it does not work out?
A June 2020 study in the journal Current Reviews in Musculoskeletal Medicine (19) offers a surgeon’s eye view of the realistic outcomes following failed shoulder surgery:
“Despite relatively high complication and reoperation rates with revision shoulder replacement, revision of failed hemiarthroplasty or total shoulder arthroplasty to reverse total shoulder arthroplasty improves outcomes for many patients. A failed hemiarthroplasty or total shoulder arthroplasty is frequently disabling for the patient and because the surgical revision options are often limited only to reverse total shoulder arthroplasty, the potential improvement is often worth the higher surgical complication or reoperation rate.”
The revision surgery is a high risk, if it works out the patient is better off. If it does not work out?
A June 2019 study in the Journal of Shoulder and Elbow Surgery (20) found good results for the revision surgery. The learning points of this study were:
- In the 110 patients involved in the study, the revision surgery implant survival was 92% at 2 years and 74% at 5 years.
- Seventy percent of patients were “very satisfied” or “satisfied with their outcome.
- Complications occurred in 18 patients (20%), and 10 patients (11%) underwent re-operation.
It is the last group of people that we usually see in our office looking for non-surgical help.
Treatment after you had shoulder replacement
In this section, we will address how we may be able to help a patient after they had shoulder replacement surgery. It makes our job here at Caring Medical a little more difficult when treating a patient who has had an extensive procedure, but it is still possible to achieve healing after surgery.
Exercise and physical therapy after reverse shoulder replacement
A January 2023 paper (21) in the Journal of shoulder and elbow surgery compared range of motion (ROM) and patient-reported outcomes (PROs) between a structured home exercise program (HEP) and active, supervised physiotherapy (PT) after primary Reverse Total Shoulder Arthroplasty. 89 patients were randomized, 43 to PT, and 46 to the home exercise program (HEP).
Patients undergoing primary Reverse Total Shoulder Arthroplasty at two medical centers were randomized to either a home exercise program group (46 patients), in which they were given a handout and a rope pulley, or a supervised physiotherapy group (43 patients), in which they were given a standardized program.
- Complications occurred in 13% of home exercise programs and 17% of supervised physiotherapy (PT) patients. Elsewise, there were no significant differences between groups at the final follow-up. These findings suggest that it may not be necessary to recommend PT as a protocol for all patients after Reverse Total Shoulder Arthroplasty.
We see many patients following failed surgery or failed physical therapy. Not every treatment will work for every patient. Some people will experience great surgical results, some will not. Some people will experience great physical therapy results, some will not. Our own treatments offered here at our center show patients who experienced outstanding outcomes, some people had good outcomes, and some people had poor outcomes. Why there are many factors to treatment success and failure.
In this video, Danielle R. Steilen-Matias, MMS, PA-C discusses treating nerve pain following shoulder surgery.
It is not uncommon for us to see patients after shoulder surgery who continue to have shoulder instability issues. Other times we will see patients after shoulder surgery who have continued pain. It may be the same pain that they had before surgery or it may be a different type of pain. What we find in many of these people is that even though healing is occurring and the shoulder looks well, the pain they are having is related to the nerves that may have been impacted during the surgery. We treat these patients with Nerve release injection therapy or more commonly hydrodissection.
Nerve Release & Regeneration Injection Therapy
NRRIT is a nerve hydrodissection technique that is highly successful in releasing peripheral nerve entrapments. It is a quick, straightforward process injection procedure often providing instant relief results for the patient! In the procedure, the practitioner uses ultrasound guidance to identify the nerves being entrapped. Next, simple dextrose is injected around the nerve to nourish the nerve and mechanically release it from the surrounding tissue, fascia, or adjacent structures.
What are we seeing in this image?
Nerve Release Injection Therapy (hydrodissection) of an entrapped nerve. In this image, a 5% dextrose solution is injected around the nerve which releases or separates it from the surrounding tissue. The nerve, which is the central circular object has a dark ring forming around it, as seen strongly in the B image. That is the dextrose solution from the needle, the straight image from the right of the screen. The nerve as seen in B is now surrounded by the nerve-release fluid and therefore “released.”
1 Morris BJ, O’Connor DP, Torres D. Risk factors for periprosthetic infection after reverse shoulder arthroplasty. J Shoulder Elbow Surg. 2014 Aug 26. pii: S1058-2746(14)00281-X. [Google Scholar]
2 Combes D, Lancigu R, de Cepoy PD, Caporilli-Razza F, Hubert L, Rony L, Aubé C. Imaging of shoulder arthroplasties and their complications: a pictorial review. Insights into imaging. 2019 Dec 1;10(1):90. [Google Scholar]
3 Mauch F, Huth J. Revision der anatomischen Schulterprothese [Revision of anatomic shoulder arthroplasty]. Orthopadie (Heidelb). 2023 Feb;52(2):137-143. German. doi: 10.1007/s00132-022-04337-3. Epub 2023 Jan 19. PMID: 36658348; PMCID: PMC9908622.
4 Malhas A, Rashid A, Copas D, Bale S, Trail I. Glenoid bone loss in primary and revision shoulder arthroplasty. Shoulder Elbow. 2016 Oct;8(4):229-40. [Google Scholar]
5 Young AA, Walch G, Pape G, Gohlke F, Favard L. Secondary rotator cuff dysfunction following total shoulder arthroplasty for primary glenohumeral osteoarthritis: results of a multicenter study with more than five years of follow-up. J Bone Joint Surg Am. 2012 Apr 18;94(8):685-93.[Google Scholar]
6 Leong NL, Sumner S, Gowd A, Nicholson GP, Romeo AA, Verma NN. Risk Factors and Complications for Revision Shoulder Arthroplasty. HSS Journal®. 2020 Feb;16(1):9-14. [Google Scholar]
7 Rasmussen JV, Olsen BS. Previous surgery for instability is a risk factor for a worse patient-reported outcome after anatomical shoulder arthroplasty for osteoarthritis: a Danish nationwide cohort study of 3,743 arthroplasties. Acta Orthopaedica. 2022;93:588. [Google Scholar]
8 Sperling JW. Pearls and Tips in Shoulder Arthroplasty. Clinics in orthopedic surgery. 2019 Sep 1;11(3):258-64. [Google Scholar]
9 Wagner ER, Houdek MT, Schleck C, Harmsen WS, Sanchez-Sotelo J, Cofield R, Sperling JW, Elhassan BT. Increasing Body Mass Index Is Associated with Worse Outcomes After Shoulder Arthroplasty. J Bone Joint Surg Am. 2017 Jun 7;99(11):929-937. [Google Scholar]
10 Murphy AB, Menendez ME, Watson SL, Ponce BA. Metabolic syndrome and shoulder arthroplasty: epidemiology and peri-operative outcomes. Int Orthop. 2016 Sep;40(9):1927-33. [Google Scholar]
11 Burns KA, Robbins LM, LeMarr AR, Fortune K, Morton DJ, Wilson ML. Modifiable risk factors increase length of stay and 90-day cost of care after shoulder arthroplasty. Journal of Shoulder and Elbow Surgery. 2022 Jan 1;31(1):2-7. [Google Scholar]
12 Reid JJ, Kunkle BF, Kothandaraman V, Roche C, Eichinger JK, Friedman RJ. Effects of obesity on clinical and functional outcomes following anatomic and reverse total shoulder arthroplasty. Journal of Shoulder and Elbow Surgery. 2022 Jan 1;31(1):17-25. [Google Scholar]
13 Riley C, Idoine J, Shishani Y, Gobezie R, Edwards B. Early Outcomes Following Metal-on-Metal Reverse Total Shoulder Arthroplasty in Patients Younger Than 50 Years. Orthopedics. 2016 Jun 23:1-5. [Google Scholar]
14 Boileau P. Complications and revision of reverse total shoulder arthroplasty. Orthop Traumatol Surg Res. 2016 Feb 12. pii: S1877-0568(15)00349-7. [Google Scholar]
15 Wittmann T, Raiss P. Revision surgery in reverse shoulder arthroplasty: Management of the most common complications. Orthopadie (Heidelberg, Germany). 2023 Jan 27. [Google Scholar]
16 Kim SC, Kim IS, Jang MC, Yoo JC. Complications of reverse shoulder arthroplasty: a concise review. Journal of the Korean Shoulder and Elbow Society. 2021 Feb 19. [Google Scholar]
17 Liu H, Huang TC, Yu H, Wang Y, Wang D, Long Z. Total shoulder arthroplasty versus reverse total shoulder arthroplasty: Outcome comparison in osteoarthritis patients with or without concurrent rotator cuff deficiency. Medicine (Baltimore). 2022 Aug 12;101(32):e29896. [Google Scholar]
18 Ravi V, Murphy RJ, Moverley R, Derias M, Phadnis J. Outcome and complications following revision shoulder arthroplasty: a systematic review and meta-analysis. Bone & Joint Open. 2021 Aug 2;2(8):618-30. [Google Scholar]
19 Harrison AK, Knudsen ML, Braman JP. Hemiarthroplasty and Total Shoulder Arthroplasty Conversion to Reverse Total Shoulder Arthroplasty [published online ahead of print, 2020 Jun 6]. Curr Rev Musculoskelet Med. 2020;10.1007/s12178-020-09649-5. doi:10.1007/s12178-020-09649-5. [Google Scholar]
20 Sheth MM, Sholder D, Getz CL, Williams GR, Namdari S. Revision of failed hemiarthroplasty and anatomic total shoulder arthroplasty to reverse total shoulder arthroplasty. J Shoulder Elbow Surg. 2019;28(6):1074-1081. doi:10.1016/j.jse.2018.10.026 [Google Scholar]
21 Chalmers PN, Tashjian R, Keener J, Sefko JA, Da Silva A, Morrissey C, Presson AP, Zhang C, Chamberlain AM. Active Physical Therapy Does Not Improve Outcomes After Reverse Total Shoulder Arthroplasty: A Multi-Center, Randomized Clinical Trial. Journal of Shoulder and Elbow Surgery. 2023 Jan 21. [Google Scholar]
This article was updated February 10, 2023