Skin Pain, Hot and Cold Skin: Are fixing upper cervical neck instability problems the missing treatment?

Ross Hauser, MD.

Like many of the people we see, people who have symptoms of tactile allodynia or painful to the touch skin, skin sensations where one half of their body will feel hot and one half of their body will feel cold, rashes and problems of sweating, will have these symptoms among a “sea of symptoms,” that can include chest pain, GERD, ear and vision issues, and neck and joint pain.

These people have so many issues, sometimes they lose track of what is affecting them and their primary concern may change over the course of days and weeks. Where today they may have nausea and that is the main concern, their swallowing difficulties will worsen to the point that that is their main concern.

Problems of the skin, symptoms of the skin, or manifestations of the skin can be caused by many problems. The focus of this article will be for people who have already had the many tests to isolate causes that have not offered a clear cut diagnosis and treatment plan beyond symptom management. In this article, we will look for the unknown cause of these skin manifestations in the upper cervical spine and how neck instability and pressure, and disruption on the neurological nerve network that passes through the neck may be the missing diagnosis for some.

The symptoms, the diagnosis, and the medical journey. These are the stories we hear.

Many of the people that contact our office have been on a long medical journey, perhaps like yourself. Years of testing, years of trial and error medicine. The one thing that many of these people have acquired is a much thicker medical file. Here are some of the stories we hear.

Ehlers-Danlos syndrome, skin flushing, sweating

I have Ehlers-Danlos syndrome, the worse pain is in my neck, then shoulders, and hips. I am told the problems in my lower legs, ankles and feet are being caused by peripheral neuropathy and I have a condition of polyneuropathy. My doctors suspect that my neck pain may be the cause of my migraines and headaches, blurred vision, eye pain, numbness, and burning sensation in my face. Some of my other doctors think that the numbness and burning sensation in my face, the problems I have with sweating (hyperhidrosis), and skin flushing, may be a problem of thoracic outlet syndrome since the skin flushing and redness is occurring mostly in my upper chest and shoulders. I have plateaued with all the treatments that are trying to manage my symptoms, I need something more.

Thoracic outlet syndrome, hot and cold, sweaty hands

My doctors tell me that my problems center around my diagnosis of Thoracic outlet syndrome. I have had a lot of surgeries. I had a scalenectomy thinking that would help with my nerve compression and symptoms. I have cervical instability C3-C7 and have been told that cervical fusion may be in order. Because the scalenectomy offered little help, I want to try to avoid the fusion. 

I have told my doctors that many of the symptoms I have including burning and tingling in my mouth, gag, and choking sensation, are related to the way I hold my head up. That is why they want to do a fusion. The symptoms that confuse my doctors the most is my ability, depending on how I stand, is to make my hands feel hot or cold, sweaty or dry, pale or red in color. They tell me that this is a neurology problem. I do not like having sweaty palms.

Changes in skin color, cold hands.

My symptoms include tingling in the mouth; pain and tingling from the neck through my hands, I have changes in skin temperature and color from white to red, a gag reflex or choking sensation, choking sensations; pressure headaches. I have a history of shoulder surgeries and a cervical fusion. I cannot get help.

Strange sensations in the skin

In the video below with Ross Hauser, MD, and Brian Hutcheson DC, a discussion of chronic skin sensations that can be common symptoms and findings in cases of cervical instability. These include symptoms like abnormal temperature regulation over half of their body or certain areas that are hot or cold compared to the rest of the body as well as specific areas that are hypersensitive or numb compared to the rest of the body, and other odd skin sensations, including localized swelling, vibration, and severe itching that have not been resolved by other traditional treatments by a dermatologist, rheumatologist, neurologist, etc.

The stories above may be a familiar tale. One of the common characteristics that you may share with these story examples is that you are getting a lot of treatments that are only addressing the symptoms. So you may be on medications for gastrointestinal distress because your swallowing difficulties may be leading to digestive problems. Your problems with sweating may begin with medications. Your headaches may be being treated with medications, you may be on medications for dizziness, you may have had Botox injections, cortisone injections, topical creams, ointments, and a shopping bag filled with other things. But nothing you are doing is helping you.

Before we move on. Many of the problems we are describing here do respond very well to conservative and traditional treatments. Many times they will succeed at a high rate and to the patient’s satisfaction. These are not the people we see at our center. We see the people who are being symptom managed without great results. Again, we will focus this article on the problem of cervical spine instability as the underlying cause for many of these problems and the symptoms of strange sensations in the skin.

Explanatory and learning points from this video are highlighted and detailed below.

What are the strange sensations in the skin that we see at our center?

The skin is a sensory organ it senses things

That the skin is reacting to some type of “bad,” neurological stimulus should not be surprising. That is what the skin does. It reacts. The skin’s reaction is a warning signal that something is not right or something is wrong. The skin is very clever, but the skin can also be confused. If you are reading this article your skin’s confusion can be in the relaying of messages from the skin, through the cervical spine into the brain. We are suggesting that there is a message interruption occurring in the neck being caused by cervical spine instability.

Senses disrupted

A brief discussion on Complex Regional Pain Syndrome and the touch/pain sensation, changes in skin color, and temperature asymmetry

For a more detailed discussion please see our more extensive article –  Complex Regional Pain Syndrome (CRPS). In this article, we will highlight a portion of that article as it relates to touch and pain sensitivity.

Many of the challenges patients with skin sensitivity to pain and temperature have many of the symptoms common in Complex Regional Pain Syndrome. These patients will also have a very heightened sensitivity to pain, especially in the skin. A cool breeze will “burn,” on their exposed skin. Bed sheets will cause a similar pain sensation when they try to sleep. Updated information in the National Center for Biotechnology Information publication STAT PEARLS (1) offers this explanation and understanding of hyperesthesia and allodynia.

“The official International Association for the Study of Pain definition of allodynia at the time of this article is “pain due to a stimulus that does not normally provoke pain.” An example would be a light feather touch (that should only produce sensation) causing pain. Allodynia is different from hyperalgesia, which is an exaggerated response from a normally painful stimulus, although both can and often do co-exist. Both are types of neuropathic pain.

An example of the difference between allodynia and hyperalgesia on the physical exam would be softly rubbing a cotton-tipped swab against a patient’s skin. Lightly brushing a swab against the skin would cause a low-level stimulus, but should not elicit a pain response. A patient who experiences pain with a stimulus that should only cause sensation may have allodynia. If the clinician significantly increases the degree of pressure, some pain would be part of a normal response. A patient who feels an excessive amount of pain would be noted to have hyperalgesia.”

Patients may display the following problems:

The problems of temperature asymmetry and cervical spine instability

In our nearly three decades in helping people with chronic pain, we have seen, from the start, that mysterious symptoms and missing diagnosis often plague people with upper cervical instability and compression of the brainstem. Solving the problem of a missing diagnosis of cervical spine issues causing these mysterious symptoms may be found in dysregulation of temperature control in the body.

Researchers as far back as 1998 published findings (2) on the value of infrared or thermovision images in pain syndromes associated with instability of the cervical segment of the spine.

In this study, 71 patients with cervical spine instability had high-temperature readings of the neck and severe cervical hyperthermia (above normal temperature readings) when compared to healthy subjects.

When the doctors addressed the cervical spine problems through therapy and rehabilitation, they could see that high dynamic changes were occurring in the patient’s temperature readings. As rehabilitation programs helped correct the neck problems, temperature symmetry (normal regulation) in the neck returned and there was a reduction of cervical hyperthermia.

The results of the study tests point to the suitability of the thermovision testing in the evaluation of the effectiveness of rehabilitation procedures in patients with cervical segments of the spine. In other words, your cervical spine treatments are working if the patient’s temperature asymmetry is correcting itself.

Where you are hot and cold could dictate where your cervical spine instability is

Here is a study (3) from 1999 that used thermal imaging to help assess possible locations neck that was causing arm pain. In this study, researchers found that symptoms of a cool or warm sensation in the arm could be shown objectively by using thermography with the detection of thermal change in the case of radiculopathy, including cervical disc herniation.

In other words, if you take the temperature of the arm, not only will temperature asymmetry, the different readings across the arm confirm a problem in the cervical spine, but the location of the problem temperatures in the arm may also give a clue to exactly where in the neck the problem was.

But this can be a tricky science, in 2020 researchers published these observations in the journal Medicine (4).

“In general, in digital infrared thermographic imaging of patients with unilateral (one-sided) spinal radicular pain, the thermal pattern of the extremities of the side of (the degenerative disc lesions) shows hypothermia (cold skin) compared to the opposite, intact side.

However, sometimes, digital infrared thermographic imaging shows hyperthermia (hot skin) on the side of the lesion, and this variation can cause confusion.”

What the researchers did was try to explain this flip-flop in temperature asymmetry.

They compared the data of both hypothermia and hyperthermia patients to clarify the factors determining different thermal characteristics in spinal radiculopathy. Two hundred twenty-four patients were divided into two groups:

A hypothermia group (180 patients) and a hyperthermia group (44 patients). Then they compared the various factors that could account for this.

They found: In patients with trauma history, acute phase of pain, and severe radicular pain, hyperthermia in digital infrared thermographic imaging is not unusual and careful interpretation of the digital infrared thermographic imaging results is necessary for proper diagnosis and treatment decisions in spinal radiculopathy.

In other words, in chronic neck pain people, hot and cold can go either way.

In chronic neck pain people, hot and cold can go either way

As we discussed above and demonstrated with independent research, understanding skin temperature can help us understand your symptoms and where these symptoms can be coming from. In other words, understanding skin temperature can help get to the underlying cause of your problems if are centered in your cervical spine and neck pain.

Checking temperatures at various points of the body

Checking temperatures at various points of the body.

The clue that temperature dysfunction is being caused by cervical spine instability

Patient demonstration at 1:45 of the above video – the clue that temperature dysfunction is being caused by cervical spine instability.

Why just one side? Why is it difficult to understand or diagnose?

No symptoms at rest or certain motion, all symptoms appear when you move your head to left or right, up or down.

For some, the missing diagnosis for skin sensitivity issues is the cervical spine

This slide explains that all the nerves that go to your arm and that go to your leg have sympathetic nerves with them that are associated with blood vessels. When the sympathetic system gets irritated that’s going to give you heat and cold sensation. The point is that any of these spinal nerves whether it’s in the leg the neck if they’re irritated it can irritate the sympathetic ganglion and vice-versa which can affect the skin

What are we seeing in this image?

A Digital Motion X-Ray or DMX is a tool we use to help understand a patient’s neck instability and how we may be able to help the patients with our treatments. In the illustration below a patient who suffered from upper cervical instability demonstrated hypermobility of the C1-C2. This hypermobility can result in common symptoms of neck pain, headaches, dizziness, vertigo, tinnitus, concentration difficulties, anxiety, skin flushes, hot skin, cold, skin, sensitivity to pain.

A Digital Motion X-Ray or DMX is a tool we use to help understand a patient' neck instability and how we may be able to help the patients with our treatments. In the illustration below a patient who suffered from upper cervical instability demonstrated hypermobility of the C1-C2. This hypermobility can result in common symptoms of neck pain, headaches, dizziness, vertigo, tinnitus, concentration difficulties, anxiety and other symptoms common in TMJ/TMD patients.

The treatment of cervical spine instability at the Hauser Neck Center – Research on cervical instability and Prolotherapy

In the above article, we suggest that many of the problems related to among other symptoms, skin sensations, and temperature regulation can be treated by addressing cervical spine instability in the neck. There are many ways to treat this problem. Our preferred choice is regenerative medicine injections that begin with Prolotherapy.

Caring Medical has published dozens of papers on Prolotherapy injections as a treatment in difficult to treat musculoskeletal disorders. Prolotherapy is an injection technique utilizing simple sugar or dextrose. Our research documents our experience with our patients.

In 2015, our research team at Caring Medical published findings in the European Journal of Preventive Medicine investigating the role of Prolotherapy in the reduction of pain and symptoms associated with increased cervical intervertebral motion, structural deformity, and irritation of nerve roots. Irritation of nerve roots causes many of the symptoms and challenges our patients face.

Twenty-one study participants were selected from patients seen for the primary complaint of neck pain. Following a series of Prolotherapy injections, patient-reported assessments were measured using questionnaire data, including range of motion (ROM), crunching, stiffness, pain level, numbness, and exercise ability, between 1 and 39 months post-treatment (average = 24 months).

We concluded that statistically significant reductions in pain and functionality, indicating the safety and viability of Prolotherapy for cervical spine instability. (5)

In 2014, we published a comprehensive review of the problems related to weakened damaged cervical neck ligaments in The Open Orthopaedics Journal. (6) We are honored that this research has been used in at least 6 other medical research papers by different authors exploring our treatments and findings and cited, according to Google Scholar, in more than 40 articles.

This is what we wrote in this paper: “To date, there is no consensus on the diagnosis of cervical spine instability or on traditional treatments that relieve chronic neck instability issues like those mentioned above. In such cases, patients often seek out alternative treatments for pain and symptom relief. Prolotherapy is one such treatment that is intended for acute and chronic musculoskeletal injuries, including those causing chronic neck pain related to underlying joint instability and ligament laxity. While these symptom classifications should be obvious signs of a patient in distress, the cause of the problems are not so obvious. Further and unfortunately, there is often no correlation between the hypermobility or subluxation of the vertebrae, clinical signs or symptoms, or neurological signs (such as excessive sweating or inability to sweat and temperature dysregulation or other skin sensations mentioned in this article) or symptoms.”

What we demonstrated in this study is that the cervical neck ligaments are the main stabilizing structures of the cervical facet joints in the cervical spine and have been implicated as a major source of chronic neck pain and in the case of many of the symptoms we mentioned above.

Summary and contact us. Can we help you? How do I know if I’m a good candidate?

We hope you found this article informative and it helped answer many of the questions you may have surrounding Skin Pain, Hot and Cold Skin. Just like you, we want to make sure you are a good fit for our clinic prior to accepting your case. While our mission is to help as many people with chronic pain as we can, sadly, we cannot accept all cases. We have a multi-step process so our team can really get to know you and your case to ensure that it sounds like you are a good fit for the unique testing and treatments that we offer here.

Please visit the Hauser Neck Center Patient Candidate Form

References for this article:

1 He Y, Kim PY. Allodynia. InStatPearls [Internet] 2019 Aug 17. StatPearls Publishing. [Google Scholar]
2 Jasiak-Tyrkalska B, Frańczuk B. Evaluation of thermovision images in pain syndrome associated with instability of the cervical segment of the spine. Przeglad Lekarski. 1998 Jan 1;55(5):246-9. [Google Scholar]
3. Zhang HY, Kim YS, Cho YE. Thermatomal changes in cervical disc herniations. Yonsei Medical Journal. 1999 Oct 1;40(5):401-12. [Google Scholar]
4. Park TY, Son S, Lim TG, Jeong T. Hyperthermia associated with spinal radiculopathy as determined by digital infrared thermographic imaging. Medicine. 2020 Mar 1;99(11):e19483. [Google Scholar]
5 Hauser RA, Steilen D, Sprague IS. Cervical Instability as a Cause of Barré-Liéou Syndrome and Definitive Treatment with Prolotherapy: A Case Series. European Journal of Preventive Medicine. 2015;3(5):155-66. [Google Scholar]
6 Steilen D, Hauser R, Woldin B, Sawyer S. Chronic neck pain: making the connection between capsular ligament laxity and cervical instability. The open orthopaedics journal. 2014;8:326.  [Google Scholar]

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